ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088179 PTPN4 9606 + 2:119759631-119983818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263708 PTPN4-001 119759631-119983818 protein_coding
  ENST00000420482 PTPN4-011 119760177-119862622 protein_coding
  ENST00000430976 PTPN4-002 119882503-119977461 nonsense_mediated_decay
  ENST00000431283 PTPN4-010 119932476-119946670 protein_coding
  ENST00000433888 PTPN4-005 119877323-119934960 nonsense_mediated_decay
  ENST00000441089 PTPN4-008 119960824-119977083 protein_coding
  ENST00000460162 PTPN4-009 119759954-119809884 processed_transcript
  ENST00000460289 PTPN4-003 119760220-119880117 processed_transcript
  ENST00000469511 PTPN4-007 119960792-119967872 retained_intron
  ENST00000485247 PTPN4-004 119760275-119882579 processed_transcript
  ENST00000488279 PTPN4-012 119760224-119882146 protein_coding
  ENST00000488896 PTPN4-006 119932280-119935104 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000263708ENST00000430976ENST00000431283ENST00000433888ENST00000441089ENST00000460289ENST00000485247
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000263708 0.221±0.00 0.902±0.92 N/A 0.967±0.00 0.876±0.70
ENST00000430976 0.488±0.00 0.800±0.38 1.167±0.00 N/A 0.889±0.39
ENST00000431283 N/A N/A N/A N/A 4.195±1.04
ENST00000433888 N/A N/A N/A 4.427±0.00 N/A
ENST00000441089 3.900±0.55 1.895±0.00 6.701±0.00 N/A 3.804±0.00
ENST00000460289 N/A N/A N/A N/A 5.459±2.09
ENST00000485247 N/A N/A N/A N/A 2.279±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00093M CIL_00093M_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0004726 IEA non-membrane spanning protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006470 TAS:IEA protein dephosphorylation
GO:0008092 IEA cytoskeletal protein binding
GO:0008138 IEA protein tyrosine/serine/threonine phosphatase activity
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0019898 IEA extrinsic component of membrane
GO:0035335 IEA peptidyl-tyrosine dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000183 ptpn4b protein_coding Danio_rerio
ENSDARG00000000631 ptpn4a protein_coding Danio_rerio
ENSMUSG00000026384 Ptpn4 protein_coding Mus_musculus

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