ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: zinc finger protein 268
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000090612 ZNF268 9606 + 12:133181409-133214831 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228289 ZNF268-002 133181474-133205023 protein_coding
  ENST00000416488 ZNF268-201 133181409-133193537 protein_coding
  ENST00000500625 ZNF268-007 133181503-133202219 protein_coding
  ENST00000534953 ZNF268-010 133191721-133202310 retained_intron
  ENST00000536435 ZNF268-001 133181409-133214831 protein_coding
  ENST00000536899 ZNF268-003 133181514-133205121 protein_coding
  ENST00000537973 ZNF268-005 133181495-133188153 retained_intron
  ENST00000539248 ZNF268-004 133181511-133202440 protein_coding
  ENST00000541009 ZNF268-012 133181559-133205173 protein_coding
  ENST00000541211 ZNF268-008 133181495-133202350 protein_coding
  ENST00000541975 ZNF268-014 133181528-133191608 protein_coding
  ENST00000542711 ZNF268-013 133181511-133202647 protein_coding
  ENST00000542986 ZNF268-009 133181514-133205173 protein_coding
  ENST00000546126 ZNF268-006 133181495-133191506 nonsense_mediated_decay
  ENST00000585488 ZNF268-017 133191455-133202169 retained_intron
  ENST00000588312 ZNF268-016 133181620-133202348 nonsense_mediated_decay
  ENST00000591951 ZNF268-018 133191497-133202440 protein_coding
  ENST00000592241 ZNF268-015 133181620-133202348 protein_coding
  ENST00000611984 ZNF268-202 133181522-133193537 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000228289ENST00000416488ENST00000536435ENST00000536899ENST00000537973ENST00000541009ENST00000542986ENST00000591951
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000228289 N/A 1.195±0.62 N/A 1.116±0.55
ENST00000416488 N/A N/A N/A 3.526±0.58
ENST00000536435 N/A 0.504±0.00 N/A 0.317±0.12
ENST00000536899 N/A 1.304±0.58 N/A 1.383±0.41
ENST00000537973 N/A N/A N/A 5.158±2.73
ENST00000541009 N/A 1.261±0.51 4.318±0.00 1.514±0.56
ENST00000542986 N/A N/A N/A 0.772±0.24
ENST00000591951 5.100±0.00 N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0003676 IEA nucleic acid binding
GO:0003677 NAS DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 NAS nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA:NAS regulation of transcription, DNA-templated
GO:0007346 IMP regulation of mitotic cell cycle
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0008588 IDA release of cytoplasmic sequestered NF-kappaB
GO:0030154 IEA cell differentiation
GO:0030335 IMP positive regulation of cell migration
GO:0043065 IMP positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043497 IDA regulation of protein heterodimerization activity
GO:0045597 IMP positive regulation of cell differentiation
GO:0045732 IDA positive regulation of protein catabolic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046022 IMP positive regulation of transcription from RNA polymerase II promoter during mitosis
GO:0046872 IEA metal ion binding
GO:0071157 IMP negative regulation of cell cycle arrest
GO:0071356 IDA cellular response to tumor necrosis factor
GO:0090073 IDA positive regulation of protein homodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075470 zgc:110238 protein_coding Danio_rerio
ENSDARG00000075834 si:dkey-182i3.8 protein_coding Danio_rerio
ENSDARG00000086182 si:dkey-54f18.1 protein_coding Danio_rerio
ENSDARG00000086720 zgc:173603 protein_coding Danio_rerio
ENSDARG00000087249 si:dkey-7i4.17 protein_coding Danio_rerio
ENSDARG00000088378 si:dkeyp-4f2.4 protein_coding Danio_rerio
ENSDARG00000090400 CR388363.1 protein_coding Danio_rerio
ENSDARG00000091524 si:ch211-162i8.3 protein_coding Danio_rerio
ENSDARG00000091793 CABZ01071911.2 protein_coding Danio_rerio
ENSDARG00000092000 si:ch211-286l10.1 protein_coding Danio_rerio
ENSDARG00000093143 si:dkey-77f5.5 protein_coding Danio_rerio
ENSDARG00000094175 si:dkey-29p23.3 protein_coding Danio_rerio
ENSDARG00000094459 si:dkey-16p19.10 protein_coding Danio_rerio
ENSDARG00000095440 si:dkeyp-53e4.2 protein_coding Danio_rerio
ENSDARG00000095708 si:dkey-77f5.16 protein_coding Danio_rerio

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