ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: angiopoietin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000091879 ANGPT2 9606 - 8:6499651-6563409 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000325203 ANGPT2-001 6499651-6563409 protein_coding
  ENST00000338312 ANGPT2-002 6503080-6563044 protein_coding
  ENST00000523120 ANGPT2-003 6507564-6563245 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000325203ENST00000338312ENST00000523120
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000325203 2.980±0.00 8.711±8.59 3.349±0.00 N/A 8.958±12.56
ENST00000338312 N/A 3.658±1.21 N/A 51.818±0.00 23.629±32.42
ENST00000523120 N/A 10.180±3.74 N/A N/A 5.938±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000LC CIL_0000LC_0001 CGP
CIL_0008KU CIL_0008KU_0001 VISTA
CIL_00006Z CIL_00006Z_0002 CGP
CIL_00006Y CIL_00006Y_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001666 IEA response to hypoxia
GO:0005102 TAS receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0007165 TAS signal transduction
GO:0007281 IEA germ cell development
GO:0007596 TAS blood coagulation
GO:0009314 IEA response to radiation
GO:0009612 IEA response to mechanical stimulus
GO:0009749 IEA response to glucose
GO:0010812 IEA negative regulation of cell-substrate adhesion
GO:0014070 IEA response to organic cyclic compound
GO:0014823 IEA response to activity
GO:0016525 IEA negative regulation of angiogenesis
GO:0030971 IPI receptor tyrosine kinase binding
GO:0031100 IEA organ regeneration
GO:0042995 IEA cell projection
GO:0043537 IDA negative regulation of blood vessel endothelial cell migration
GO:0045766 IEA positive regulation of angiogenesis
GO:0046872 IEA metal ion binding
GO:0048014 IDA Tie signaling pathway
GO:0048514 IEA blood vessel morphogenesis
GO:0050900 TAS leukocyte migration
GO:0050928 IDA negative regulation of positive chemotaxis
GO:0060135 IEA maternal process involved in female pregnancy
GO:0071363 IEA cellular response to growth factor stimulus
GO:0072012 ISS glomerulus vasculature development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014946 angpt2a protein_coding Danio_rerio
ENSMUSG00000031465 Angpt2 protein_coding Mus_musculus

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