ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: THO complex 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100296 THOC5 9606 - 22:29505879-29555216 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358079 THOC5-005 29508331-29549157 nonsense_mediated_decay
  ENST00000397871 THOC5-201 29508168-29553655 protein_coding
  ENST00000397872 THOC5-202 29508168-29553655 protein_coding
  ENST00000397873 THOC5-004 29508358-29553766 protein_coding
  ENST00000414902 THOC5-012 29543429-29553741 nonsense_mediated_decay
  ENST00000418021 THOC5-009 29543503-29555216 protein_coding
  ENST00000428374 THOC5-008 29539444-29553680 protein_coding
  ENST00000440771 THOC5-010 29536667-29553655 protein_coding
  ENST00000442555 THOC5-002 29508327-29554254 nonsense_mediated_decay
  ENST00000443089 THOC5-015 29525838-29542888 protein_coding
  ENST00000455450 THOC5-013 29539338-29545144 protein_coding
  ENST00000472164 THOC5-017 29508329-29511442 retained_intron
  ENST00000475187 THOC5-007 29534538-29549144 retained_intron
  ENST00000484924 THOC5-016 29519006-29536738 retained_intron
  ENST00000488052 THOC5-014 29531553-29536738 retained_intron
  ENST00000490103 THOC5-001 29505879-29553782 protein_coding
  ENST00000492707 THOC5-003 29528383-29539469 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000397871ENST00000397872ENST00000397873ENST00000442555ENST00000472164ENST00000490103
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000397871 8.606±0.00 7.411±1.29 3.402±0.00 4.045±0.00 16.354±0.00
ENST00000397872 N/A N/A N/A N/A 5.207±0.86
ENST00000397873 10.383±0.11 10.131±3.49 N/A 4.303±0.00 10.388±4.85
ENST00000442555 N/A N/A N/A N/A 4.472±0.09
ENST00000472164 54.071±19.18 N/A 20.261±0.00 N/A N/A
ENST00000490103 N/A 1.760±0.06 N/A N/A 2.758±1.70

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000346 IDA transcription export complex
GO:0000347 IDA THO complex
GO:0000445 IDA THO complex part of transcription export complex
GO:0000902 IEA cell morphogenesis
GO:0001824 IEA blastocyst development
GO:0003729 IEA mRNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006397 IEA mRNA processing
GO:0006406 IDA mRNA export from nucleus
GO:0008380 IEA RNA splicing
GO:0010468 IEA regulation of gene expression
GO:0010793 IEA regulation of mRNA export from nucleus
GO:0017145 IEA stem cell division
GO:0030224 IDA monocyte differentiation
GO:0032786 IMP positive regulation of DNA-templated transcription, elongation
GO:0045650 IEA negative regulation of macrophage differentiation
GO:0046784 IDA viral mRNA export from host cell nucleus
GO:0060215 ISS primitive hemopoiesis
GO:2000002 IMP negative regulation of DNA damage checkpoint
GO:2000035 IEA regulation of stem cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038290 thoc5 protein_coding Danio_rerio
ENSMUSG00000034274 Thoc5 protein_coding Mus_musculus

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