ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100567 PSMA3 9606 + 14:58244831-58272012 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216455 PSMA3-001 58244831-58272007 protein_coding
  ENST00000412908 PSMA3-002 58244877-58272012 protein_coding
  ENST00000553665 PSMA3-008 58244856-58258454 retained_intron
  ENST00000553677 PSMA3-007 58257925-58272006 protein_coding
  ENST00000554207 PSMA3-005 58263524-58267796 retained_intron
  ENST00000554456 PSMA3-014 58244874-58245478 processed_transcript
  ENST00000554812 PSMA3-006 58244846-58268139 retained_intron
  ENST00000555743 PSMA3-016 58244879-58267528 retained_intron
  ENST00000555931 PSMA3-011 58244873-58267504 nonsense_mediated_decay
  ENST00000556321 PSMA3-015 58247789-58258081 retained_intron
  ENST00000557087 PSMA3-012 58244866-58270998 nonsense_mediated_decay
  ENST00000557290 PSMA3-004 58269975-58272004 retained_intron
  ENST00000557508 PSMA3-013 58244904-58272007 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000216455ENST00000412908ENST00000553665ENST00000553677ENST00000554456ENST00000554812ENST00000555743ENST00000557087ENST00000557290ENST00000557508
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000216455 25.423±6.54 32.482±10.83 N/A 54.430±0.00 50.669±30.76
ENST00000412908 N/A 8.046±0.01 N/A 29.600±0.00 N/A
ENST00000553665 N/A N/A N/A N/A 0.813±0.00
ENST00000553677 146.519±60.24 68.082±11.42 430.614±0.00 N/A N/A
ENST00000554456 N/A N/A N/A N/A 2.025±0.00
ENST00000554812 N/A N/A N/A N/A 0.978±0.27
ENST00000555743 26.978±0.00 29.909±6.44 N/A 51.169±0.00 54.825±52.82
ENST00000557087 28.133±0.00 14.868±0.01 N/A N/A 15.011±14.19
ENST00000557290 N/A N/A N/A N/A 2.175±0.24
ENST00000557508 45.964±2.98 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00022F CIL_00022F_0001 CGP
CIL_0001K7 CIL_0001K7_0001 CGP
CIL_0004LX CIL_0004LX_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004175 IEA endopeptidase activity
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005839 IDA:IEA proteasome core complex
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019773 IEA proteasome core complex, alpha-subunit complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086618 psma3 protein_coding Danio_rerio
ENSMUSG00000060073 Psma3 protein_coding Mus_musculus

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