ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, ATPase, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100764 PSMC1 9606 + 14:90256495-90275429 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261303 PSMC1-001 90256495-90275429 protein_coding
  ENST00000543772 PSMC1-002 90256578-90272550 protein_coding
  ENST00000553835 PSMC1-004 90256527-90268274 protein_coding
  ENST00000554624 PSMC1-005 90256528-90263670 retained_intron
  ENST00000555679 PSMC1-006 90256554-90263944 retained_intron
  ENST00000555787 PSMC1-003 90267476-90272624 retained_intron
  ENST00000557357 PSMC1-007 90256554-90263927 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000543772ENST00000554624ENST00000555679ENST00000557357
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000543772 35.277±3.78 14.711±4.15 11.606±0.00 16.094±0.00 17.161±10.78
ENST00000554624 N/A N/A N/A N/A 30.704±0.00
ENST00000555679 N/A 20.217±5.07 N/A 33.055±0.00 59.229±39.40
ENST00000557357 N/A N/A N/A N/A 55.847±14.55

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002L5 CIL_0002L5_0002 CGP
CIL_0001JW CIL_0001JW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005838 IEA proteasome regulatory particle
GO:0006200 ISS ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0009378 IEA four-way junction helicase activity
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016787 IEA hydrolase activity
GO:0016887 ISS ATPase activity
GO:0017025 IEA TBP-class protein binding
GO:0022624 ISS proteasome accessory complex
GO:0030163 IEA protein catabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030537 psmc1a protein_coding Danio_rerio
ENSDARG00000043561 psmc1b protein_coding Danio_rerio
ENSMUSG00000021178 Psmc1 protein_coding Mus_musculus

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