ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Rho GTPase activating protein 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100852 ARHGAP5 9606 + 14:32076114-32159728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216743 ARHGAP5-005 32154010-32157216 retained_intron
  ENST00000345122 ARHGAP5-201 32077289-32159728 protein_coding
  ENST00000396582 ARHGAP5-003 32077074-32159728 protein_coding
  ENST00000432921 ARHGAP5-202 32077289-32155138 protein_coding
  ENST00000433497 ARHGAP5-004 32077309-32157079 protein_coding
  ENST00000539826 ARHGAP5-001 32076985-32155083 protein_coding
  ENST00000554090 ARHGAP5-008 32078231-32154633 protein_coding
  ENST00000555814 ARHGAP5-006 32076114-32090780 protein_coding
  ENST00000556191 ARHGAP5-007 32078231-32091089 protein_coding
  ENST00000556611 ARHGAP5-002 32076967-32155011 protein_coding
  ENST00000557643 ARHGAP5-009 32094038-32154827 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000216743ENST00000345122ENST00000432921ENST00000433497ENST00000539826ENST00000556611
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000216743 1.075±0.56 N/A N/A 0.971±0.40
ENST00000345122 0.089±0.00 1.285±1.12 1.352±0.00 1.163±0.67
ENST00000432921 N/A 0.169±0.00 N/A 1.034±0.68
ENST00000433497 N/A 0.950±0.58 3.355±0.00 3.355±2.63
ENST00000539826 N/A 1.787±1.98 4.338±0.00 2.402±2.15
ENST00000556611 N/A 2.305±1.71 N/A 1.858±1.39

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005RC CIL_0005RC_0002 CGP
CIL_0000H7 CIL_0000H7_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0003924 TAS GTPase activity
GO:0005100 TAS Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006184 TAS GTP catabolic process
GO:0007155 TAS cell adhesion
GO:0007165 IEA signal transduction
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007266 TAS Rho protein signal transduction
GO:0008361 IEA regulation of cell size
GO:0016020 IEA membrane
GO:0030335 IEA positive regulation of cell migration
GO:0030879 IEA mammary gland development
GO:0032321 TAS positive regulation of Rho GTPase activity
GO:0042169 IPI SH2 domain binding
GO:0051056 TAS regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061294 arhgap5 protein_coding Danio_rerio
ENSMUSG00000035133 Arhgap5 protein_coding Mus_musculus

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