ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101557 USP14 9606 + 18:158383-214629 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261601 USP14-003 158608-214629 protein_coding
  ENST00000383589 USP14-004 158591-211997 protein_coding
  ENST00000400266 USP14-002 158536-211350 protein_coding
  ENST00000578786 USP14-008 196539-211268 retained_intron
  ENST00000578942 USP14-005 158561-212601 retained_intron
  ENST00000580410 USP14-006 158557-163431 protein_coding
  ENST00000581983 USP14-007 158858-163454 protein_coding
  ENST00000582707 USP14-001 158383-211391 protein_coding
  ENST00000583119 USP14-009 163393-198110 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000261601ENST00000383589ENST00000400266ENST00000578942ENST00000582707ENST00000583119
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000261601 N/A 12.640±2.70 11.786±0.00 7.209±3.35
ENST00000383589 9.096±3.85 32.296±3.69 24.242±0.00 17.736±8.41
ENST00000400266 N/A 13.545±1.48 N/A 8.413±4.98
ENST00000578942 2.418±0.00 N/A N/A 6.395±3.50
ENST00000582707 N/A N/A N/A 10.632±4.98
ENST00000583119 N/A N/A N/A 39.513±8.83

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0004866 IMP endopeptidase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007268 IEA synaptic transmission
GO:0008193 TAS tRNA guanylyltransferase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0009986 IDA cell surface
GO:0010951 IMP negative regulation of endopeptidase activity
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016579 IDA protein deubiquitination
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0045202 IEA synapse
GO:0050920 IMP regulation of chemotaxis
GO:0061136 IMP regulation of proteasomal protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070628 IDA proteasome binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025889 usp14 protein_coding Danio_rerio
ENSMUSG00000047879 Usp14 protein_coding Mus_musculus

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