ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: X-linked inhibitor of apoptosis
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101966 XIAP 9606 + X:123859724-123913979 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355640 XIAP-009 123860272-123913965 protein_coding
  ENST00000371199 XIAP-002 123860027-123913979 protein_coding
  ENST00000422098 XIAP-007 123859724-123885711 protein_coding
  ENST00000430625 XIAP-005 123859878-123886130 protein_coding
  ENST00000434753 XIAP-201 123859812-123913976 protein_coding
  ENST00000468503 XIAP-010 123860454-123888683 processed_transcript
  ENST00000468691 XIAP-001 123859877-123907251 processed_transcript
  ENST00000481776 XIAP-003 123859764-123907020 processed_transcript
  ENST00000496602 XIAP-006 123912760-123913615 processed_transcript
  ENST00000497640 XIAP-004 123860195-123906998 processed_transcript
  ENST00000497906 XIAP-008 123859827-123900566 processed_transcript

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000355640ENST00000371199ENST00000434753ENST00000496602
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000355640 N/A N/A N/A N/A 0.617±0.18
ENST00000371199 0.652±0.00 1.848±1.51 N/A 6.114±0.00 3.509±2.80
ENST00000434753 1.179±0.00 0.933±0.55 N/A N/A 1.477±0.69
ENST00000496602 12.036±3.60 2.097±0.00 18.511±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000GB CIL_0000GB_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006974 IEP cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0016055 IEA Wnt signaling pathway
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030510 TAS regulation of BMP signaling pathway
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0042127 TAS regulation of cell proliferation
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045088 TAS regulation of innate immune response
GO:0050727 TAS regulation of inflammatory response
GO:0055070 TAS copper ion homeostasis
GO:0070424 TAS regulation of nucleotide-binding oligomerization domain containing signaling pathway
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1902530 IDA positive regulation of protein linear polyubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016143 xiap protein_coding Danio_rerio

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