ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sodium leak channel, non-selective
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102452 NALCN 9606 - 13:101053776-101416492 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000251127 NALCN-001 101053776-101416355 protein_coding
  ENST00000376200 NALCN-201 101368545-101399154 protein_coding
  ENST00000467264 NALCN-004 101116440-101143221 processed_transcript
  ENST00000470333 NALCN-003 101180373-101416492 processed_transcript
  ENST00000497170 NALCN-002 101142743-101416462 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000251127ENST00000376200ENST00000497170
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000251127 0.110±0.08 0.555±0.29 0.026±0.00 0.325±0.21
ENST00000376200 1.264±0.00 0.938±0.23 0.143±0.00 0.677±0.30
ENST00000497170 N/A 1.593±0.00 N/A 0.483±0.19

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000WK CIL_0000WK_0001 CGP
CIL_0004G3 CIL_0004G3_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005245 IBA voltage-gated calcium channel activity
GO:0005272 TAS sodium channel activity
GO:0005515 IPI protein binding
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0008219 IEA cell death
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0034220 TAS ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0055085 TAS:IEA transmembrane transport
GO:0070509 IBA calcium ion import
GO:0070588 IBA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001835 nalcn protein_coding Danio_rerio
ENSMUSG00000000197 Nalcn protein_coding Mus_musculus

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