ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dihydroorotate dehydrogenase (quinone)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102967 DHODH 9606 + 16:72008588-72027664 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219240 DHODH-201 72008744-72025416 protein_coding
  ENST00000571288 DHODH-004 72008778-72017079 nonsense_mediated_decay
  ENST00000571392 DHODH-001 72015623-72024512 retained_intron
  ENST00000572003 DHODH-006 72014419-72021231 retained_intron
  ENST00000572887 DHODH-002 72008588-72027664 protein_coding
  ENST00000573843 DHODH-005 72014451-72021192 retained_intron
  ENST00000573922 DHODH-008 72012233-72023278 processed_transcript
  ENST00000574309 DHODH-009 72008769-72024238 protein_coding
  ENST00000576145 DHODH-003 72008801-72017106 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000219240ENST00000571392ENST00000572887ENST00000573922ENST00000574309
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000219240 2.071±1.40 1.814±0.65 1.869±0.00 1.468±0.00 1.179±0.68
ENST00000571392 0.971±0.00 0.465±0.17 N/A 0.475±0.00 0.426±0.20
ENST00000572887 N/A 0.333±0.18 N/A 0.463±0.00 0.400±0.16
ENST00000573922 N/A N/A N/A 4.233±0.00 N/A
ENST00000574309 N/A 2.599±0.68 N/A N/A 1.895±0.43

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00098E CIL_00098E_0001 VISTA
CIL_00098B CIL_00098B_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004152 TAS:IEA dihydroorotate dehydrogenase activity
GO:0005739 IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006206 TAS pyrimidine nucleobase metabolic process
GO:0006207 IEA 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006222 IEA UMP biosynthetic process
GO:0007565 IEA female pregnancy
GO:0007595 IEA lactation
GO:0008144 IEA drug binding
GO:0010181 IEA FMN binding
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0031000 IEA response to caffeine
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0043025 IEA neuronal cell body
GO:0043065 IEA positive regulation of apoptotic process
GO:0044205 IEA 'de novo' UMP biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046134 TAS pyrimidine nucleoside biosynthetic process
GO:0048039 IEA ubiquinone binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0090140 IEA regulation of mitochondrial fission

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051889 dhodh protein_coding Danio_rerio
ENSMUSG00000031730 Dhodh protein_coding Mus_musculus

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