ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Mediterranean fever
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103313 MEFV 9606 - 16:3242028-3256627 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219596 MEFV-001 3242028-3256627 protein_coding
  ENST00000339854 MEFV-010 3242028-3256627 protein_coding
  ENST00000536379 MEFV-004 3243141-3256587 protein_coding
  ENST00000536980 MEFV-009 3242028-3256627 nonsense_mediated_decay
  ENST00000537682 MEFV-006 3242028-3256627 nonsense_mediated_decay
  ENST00000538326 MEFV-007 3242028-3256627 nonsense_mediated_decay
  ENST00000539145 MEFV-003 3243141-3256587 nonsense_mediated_decay
  ENST00000539154 MEFV-005 3246410-3247967 retained_intron
  ENST00000541159 MEFV-002 3243141-3256587 protein_coding
  ENST00000542898 MEFV-008 3242028-3256627 nonsense_mediated_decay
  ENST00000570511 MEFV-015 3243141-3256587 nonsense_mediated_decay
  ENST00000572244 MEFV-012 3243141-3256587 nonsense_mediated_decay
  ENST00000574583 MEFV-014 3243141-3256587 nonsense_mediated_decay
  ENST00000576315 MEFV-013 3243141-3256587 nonsense_mediated_decay
  ENST00000621655 MEFV-201 3243141-3256587 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000219596ENST00000339854ENST00000536980ENST00000538326ENST00000539145ENST00000539154ENST00000570511ENST00000572244
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000219596 N/A 0.044±0.00 N/A 0.146±0.00 0.019±0.00
ENST00000339854 0.053±0.00 0.047±0.04 0.486±0.00 N/A 0.024±0.02
ENST00000536980 N/A 0.003±0.00 N/A N/A 0.001±0.00
ENST00000538326 N/A N/A 0.101±0.00 N/A 0.057±0.06
ENST00000539145 N/A N/A N/A N/A 0.023±0.00
ENST00000539154 N/A 0.086±0.03 N/A N/A 0.052±0.00
ENST00000570511 N/A 0.010±0.00 N/A N/A 0.014±0.00
ENST00000572244 N/A 0.176±0.00 N/A N/A 0.028±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00029F CIL_00029F_0002 CGP
CIL_0001SW CIL_0001SW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IDA actin binding
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005874 IEA microtubule
GO:0005875 IDA microtubule associated complex
GO:0006954 IDA inflammatory response
GO:0008270 NAS:IEA zinc ion binding
GO:0032691 IMP negative regulation of interleukin-1 beta production
GO:0032695 IMP negative regulation of interleukin-12 production
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0042995 IEA cell projection
GO:0045087 TAS innate immune response
GO:0050728 IMP negative regulation of inflammatory response
GO:0071641 IMP negative regulation of macrophage inflammatory protein 1 alpha production
GO:2001056 IDA positive regulation of cysteine-type endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069407 zgc:194990 protein_coding Danio_rerio
ENSDARG00000079703 si:dkey-18p12.4 protein_coding Danio_rerio
ENSDARG00000090930 si:ch211-120g10.1 protein_coding Danio_rerio
ENSDARG00000092931 si:ch211-114c12.5 protein_coding Danio_rerio
ENSDARG00000096739 si:ch211-222b21.3 protein_coding Danio_rerio
ENSMUSG00000022534 Mefv protein_coding Mus_musculus

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