ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: heme oxygenase (decycling) 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103415 HMOX2 9606 + 16:4474690-4510347 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219700 HMOX2-004 4476379-4510346 protein_coding
  ENST00000398595 HMOX2-003 4495858-4509901 protein_coding
  ENST00000406590 HMOX2-201 4474703-4510346 protein_coding
  ENST00000414777 HMOX2-202 4495858-4510346 protein_coding
  ENST00000458134 HMOX2-002 4476340-4510295 protein_coding
  ENST00000570445 HMOX2-011 4476459-4508197 protein_coding
  ENST00000570622 HMOX2-012 4508059-4509779 protein_coding
  ENST00000570646 HMOX2-001 4475924-4510347 protein_coding
  ENST00000572812 HMOX2-008 4476412-4507838 protein_coding
  ENST00000574466 HMOX2-007 4476412-4507900 protein_coding
  ENST00000574594 HMOX2-013 4476442-4496762 processed_transcript
  ENST00000575051 HMOX2-005 4474690-4509430 protein_coding
  ENST00000575120 HMOX2-006 4476406-4509836 protein_coding
  ENST00000575129 HMOX2-010 4495858-4507904 protein_coding
  ENST00000576827 HMOX2-009 4476439-4507902 protein_coding
  ENST00000613539 HMOX2-203 4496146-4510346 protein_coding
  ENST00000619528 HMOX2-204 4476340-4510346 protein_coding
  ENST00000619913 HMOX2-205 4476340-4510346 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000219700ENST00000406590ENST00000570445ENST00000570646ENST00000572812ENST00000575120ENST00000613539
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000219700 75.322±6.98 27.088±6.80 18.511±0.00 16.756±0.00 10.750±5.41
ENST00000406590 N/A N/A N/A N/A 19.431±0.00
ENST00000570445 N/A N/A N/A N/A 31.502±9.33
ENST00000570646 N/A 11.033±2.11 N/A N/A 15.754±8.61
ENST00000572812 N/A N/A N/A N/A 36.362±5.74
ENST00000575120 129.282±11.72 64.131±18.17 20.173±0.00 39.164±0.00 28.682±14.10
ENST00000613539 N/A 20.012±0.03 N/A N/A 21.158±24.77

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002BN CIL_0002BN_0001 CGP
CIL_00009E CIL_00009E_0001 CGP
CIL_0000TZ CIL_0000TZ_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0004392 IEA:IDA heme oxygenase (decyclizing) activity
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0006778 TAS porphyrin-containing compound metabolic process
GO:0006788 IEA heme oxidation
GO:0006879 TAS cellular iron ion homeostasis
GO:0006979 IEA response to oxidative stress
GO:0016020 IDA membrane
GO:0042167 TAS heme catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055085 TAS transmembrane transport
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055101 hmox2a protein_coding Danio_rerio
ENSDARG00000078452 hmox2b protein_coding Danio_rerio
ENSMUSG00000004070 Hmox2 protein_coding Mus_musculus

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