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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin protein ligase E3 component n-recognin 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104517 UBR5 9606 - 8:102253012-102412841 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000220959 UBR5-002 102253736-102412689 protein_coding
  ENST00000517465 UBR5-012 102253946-102261986 retained_intron
  ENST00000518145 UBR5-007 102345896-102347000 retained_intron
  ENST00000518205 UBR5-004 102254198-102272931 protein_coding
  ENST00000519365 UBR5-008 102298867-102305257 protein_coding
  ENST00000519528 UBR5-014 102287505-102293709 processed_transcript
  ENST00000520539 UBR5-001 102253012-102412841 protein_coding
  ENST00000520898 UBR5-009 102298860-102305182 protein_coding
  ENST00000521312 UBR5-011 102265208-102267435 retained_intron
  ENST00000521566 UBR5-013 102271194-102276820 protein_coding
  ENST00000521767 UBR5-010 102265203-102268718 retained_intron
  ENST00000521922 UBR5-003 102254198-102412759 protein_coding
  ENST00000522327 UBR5-006 102359652-102361209 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000220959ENST00000517465ENST00000520539ENST00000521922
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000220959 N/A 4.310±1.08 N/A 8.135±0.00 2.542±1.60
ENST00000517465 7.276±1.45 N/A 18.765±0.00 N/A N/A
ENST00000520539 0.322±0.07 4.592±3.17 N/A 4.296±0.00 3.986±2.49
ENST00000521922 N/A 3.659±1.47 N/A N/A 3.362±1.47

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00000S CIL_00000S_0001 CGP
CIL_00000U CIL_00000U_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0003723 IEA RNA binding
GO:0004842 IEA:TAS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IBA cytoplasm
GO:0006281 IEA DNA repair
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0008283 TAS cell proliferation
GO:0016020 IDA membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0033160 IMP positive regulation of protein import into nucleus, translocation
GO:0034450 IDA ubiquitin-ubiquitin ligase activity
GO:0035413 IMP positive regulation of catenin import into nucleus
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043130 IEA ubiquitin binding
GO:0050847 IDA progesterone receptor signaling pathway
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:1901315 IMP negative regulation of histone H2A K63-linked ubiquitination
GO:2000780 IMP negative regulation of double-strand break repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018192 ubr5 protein_coding Danio_rerio
ENSMUSG00000037487 Ubr5 protein_coding Mus_musculus

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