ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104783 KCNN4 9606 - 19:43766533-43781257 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262888 KCNN4-001 43766533-43781257 protein_coding
  ENST00000597184 KCNN4-012 43766822-43769157 retained_intron
  ENST00000598836 KCNN4-010 43766586-43769827 protein_coding
  ENST00000599107 KCNN4-008 43774219-43776826 retained_intron
  ENST00000599720 KCNN4-007 43766953-43780976 nonsense_mediated_decay
  ENST00000600408 KCNN4-009 43767577-43772107 nonsense_mediated_decay
  ENST00000600909 KCNN4-013 43766533-43768977 protein_coding
  ENST00000601549 KCNN4-011 43767452-43772127 retained_intron
  ENST00000615047 KCNN4-201 43766533-43781257 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262888ENST00000597184ENST00000598836ENST00000599107ENST00000599720ENST00000600408ENST00000600909ENST00000601549ENST00000615047
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262888 0.105±0.00 0.314±0.14 N/A N/A 0.194±0.10
ENST00000597184 2.430±0.00 0.423±0.19 N/A N/A 0.222±0.12
ENST00000598836 5.042±0.00 0.631±0.00 0.104±0.00 0.540±0.00 0.071±0.05
ENST00000599107 N/A 0.342±0.00 N/A N/A 0.070±0.02
ENST00000599720 N/A 0.208±0.07 N/A N/A 0.137±0.12
ENST00000600408 N/A N/A N/A 1.348±0.00 N/A
ENST00000600909 N/A 0.212±0.00 N/A N/A 0.077±0.06
ENST00000601549 N/A N/A 0.072±0.00 N/A 0.012±0.01
ENST00000615047 N/A 0.226±0.15 0.097±0.00 0.622±0.00 0.112±0.07

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0005267 IEA potassium channel activity
GO:0005515 IPI protein binding
GO:0005516 IEA:IBA calmodulin binding
GO:0005886 IBA plasma membrane
GO:0006813 TAS:IEA potassium ion transport
GO:0006816 IDA calcium ion transport
GO:0006820 IEA anion transport
GO:0006884 IEA cell volume homeostasis
GO:0006952 TAS defense response
GO:0007268 TAS synaptic transmission
GO:0008076 IC voltage-gated potassium channel complex
GO:0015269 IDA:IEA calcium-activated potassium channel activity
GO:0016021 IEA integral component of membrane
GO:0016286 IEA small conductance calcium-activated potassium channel activity
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019903 IPI protein phosphatase binding
GO:0022894 IBA Intermediate conductance calcium-activated potassium channel activity
GO:0030322 IDA stabilization of membrane potential
GO:0043025 IBA neuronal cell body
GO:0045121 IEA membrane raft
GO:0045332 IEA phospholipid translocation
GO:0046541 IEA saliva secretion
GO:0050714 IEA positive regulation of protein secretion
GO:0050862 IDA positive regulation of T cell receptor signaling pathway
GO:0071435 IEA potassium ion export
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086091 kcnn4 protein_coding Danio_rerio
ENSMUSG00000054342 Kcnn4 protein_coding Mus_musculus

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