ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: amino-terminal enhancer of split
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104964 AES 9606 - 19:3052910-3063107 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000221561 AES-001 3052910-3063107 protein_coding
  ENST00000327141 AES-003 3053162-3062557 protein_coding
  ENST00000585557 AES-008 3054023-3062410 nonsense_mediated_decay
  ENST00000585782 AES-007 3057440-3062277 retained_intron
  ENST00000586003 AES-010 3060952-3062234 retained_intron
  ENST00000586742 AES-004 3052983-3062883 protein_coding
  ENST00000586839 AES-009 3053591-3061404 protein_coding
  ENST00000587083 AES-011 3054168-3056679 retained_intron
  ENST00000587393 AES-005 3053212-3057748 retained_intron
  ENST00000590067 AES-013 3053549-3056196 retained_intron
  ENST00000592330 AES-012 3053408-3062190 processed_transcript
  ENST00000592414 AES-006 3052910-3056768 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000221561ENST00000327141ENST00000585557ENST00000586839ENST00000587393ENST00000592330ENST00000592414
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000221561 N/A 3.220±0.00 N/A N/A 43.559±38.96
ENST00000327141 N/A 11.316±0.45 N/A N/A 69.912±61.93
ENST00000585557 N/A N/A N/A N/A 91.890±0.00
ENST00000586839 N/A 12.099±1.44 N/A N/A 53.050±47.51
ENST00000587393 500.325±28.47 102.498±67.24 208.844±0.00 114.921±0.00 109.343±72.72
ENST00000592330 N/A 482.951±314.95 N/A 413.169±0.00 428.092±172.81
ENST00000592414 N/A N/A N/A N/A 2.987±2.60

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005QO CIL_0005QO_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001501 IEA skeletal system development
GO:0003714 IPI transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007275 TAS multicellular organismal development
GO:0009887 TAS organ morphogenesis
GO:0010629 IMP negative regulation of gene expression
GO:0016055 IEA Wnt signaling pathway
GO:0031668 IEA cellular response to extracellular stimulus
GO:0032091 IDA negative regulation of protein binding
GO:0040008 IEA regulation of growth
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0060761 IMP negative regulation of response to cytokine stimulus
GO:0070555 IDA response to interleukin-1
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:2000210 IMP positive regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019588 chico protein_coding Danio_rerio
ENSDARG00000021805 aes protein_coding Danio_rerio
ENSMUSG00000054452 Aes protein_coding Mus_musculus

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