ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: deoxyribonuclease II, lysosomal
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105612 DNASE2 9606 - 19:12875211-12881468 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222219 DNASE2-001 12875211-12881468 protein_coding
  ENST00000586547 DNASE2-003 12878038-12878834 retained_intron
  ENST00000588777 DNASE2-004 12875936-12878680 retained_intron
  ENST00000592506 DNASE2-002 12876254-12881466 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000222219ENST00000588777ENST00000592506
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000222219 14.344±8.15 13.109±4.93 1.092±0.00 18.124±0.00 15.812±10.56
ENST00000588777 N/A 8.761±1.46 N/A 8.882±0.00 1.924±1.29
ENST00000592506 N/A N/A N/A N/A 3.828±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007VV CIL_0007VV_0001 VISTA
CIL_0007ZV CIL_0007ZV_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003677 TAS DNA binding
GO:0004520 IEA endodeoxyribonuclease activity
GO:0004531 IBA:IEA deoxyribonuclease II activity
GO:0005622 IBA intracellular
GO:0005764 IEA lysosome
GO:0006259 TAS:IEA DNA metabolic process
GO:0006308 IEA DNA catabolic process
GO:0006309 IBA apoptotic DNA fragmentation
GO:0030218 IEA erythrocyte differentiation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073893 dnase2 protein_coding Danio_rerio
ENSMUSG00000003812 Dnase2a protein_coding Mus_musculus

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