ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: integrin, beta 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105855 ITGB8 9606 + 7:20330702-20415754 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222573 ITGB8-001 20331123-20415754 protein_coding
  ENST00000460204 ITGB8-003 20331977-20353357 processed_transcript
  ENST00000477859 ITGB8-002 20364645-20382081 retained_intron
  ENST00000478974 ITGB8-004 20331102-20399062 retained_intron
  ENST00000537992 ITGB8-005 20330702-20410330 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000222573ENST00000477859ENST00000478974ENST00000537992
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000222573 0.127±0.00 0.545±0.37 0.068±0.00 1.508±0.00 2.195±2.61
ENST00000477859 0.048±0.00 0.062±0.00 0.094±0.00 N/A 0.076±0.00
ENST00000478974 N/A N/A N/A N/A 0.399±0.00
ENST00000537992 N/A 0.200±0.01 N/A N/A 1.207±0.72

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001573 IEA ganglioside metabolic process
GO:0004872 IEA receptor activity
GO:0005102 IEA receptor binding
GO:0005886 TAS plasma membrane
GO:0007155 TAS cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008305 TAS integrin complex
GO:0009986 IDA cell surface
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0016020 IEA membrane
GO:0030198 TAS extracellular matrix organization
GO:0034686 IDA integrin alphav-beta8 complex
GO:0051216 IMP cartilage development
GO:0060674 TAS placenta blood vessel development
GO:0070062 IDA extracellular vesicular exosome
GO:1990430 IDA extracellular matrix protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028222 itgb8 protein_coding Danio_rerio
ENSMUSG00000025321 Itgb8 protein_coding Mus_musculus

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