ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105953 OGDH 9606 + 7:44606572-44709066 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222673 OGDH-001 44606639-44709066 protein_coding
  ENST00000419661 OGDH-008 44606595-44666851 protein_coding
  ENST00000439616 OGDH-005 44606572-44708230 protein_coding
  ENST00000443864 OGDH-007 44606588-44676594 protein_coding
  ENST00000444676 OGDH-006 44606628-44708138 protein_coding
  ENST00000447398 OGDH-003 44606591-44708278 protein_coding
  ENST00000449767 OGDH-002 44606591-44708328 protein_coding
  ENST00000459672 OGDH-009 44666621-44675245 processed_transcript
  ENST00000497326 OGDH-010 44666795-44674752 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000222673ENST00000439616ENST00000443864ENST00000444676ENST00000449767
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000222673 6.751±0.00 27.161±10.39 1.974±0.00 23.080±0.00 19.609±12.51
ENST00000439616 N/A 12.022±4.45 N/A 7.310±0.00 4.158±2.23
ENST00000443864 N/A 4.168±0.21 N/A N/A 0.659±0.00
ENST00000444676 N/A 6.854±0.01 N/A N/A 5.973±0.45
ENST00000449767 N/A 6.124±1.66 N/A N/A 5.778±2.94

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000J7 CIL_0000J7_0001 CGP
CIL_0000J8 CIL_0000J8_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004591 IEA:ISS oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006091 ISS generation of precursor metabolites and energy
GO:0006096 IEA glycolytic process
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0006103 IEA 2-oxoglutarate metabolic process
GO:0006104 IEA succinyl-CoA metabolic process
GO:0006554 TAS lysine catabolic process
GO:0006734 IEA NADH metabolic process
GO:0008152 IEA metabolic process
GO:0016624 IEA oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0021695 IEA cerebellar cortex development
GO:0021756 IEA striatum development
GO:0021766 IEA hippocampus development
GO:0021794 IEA thalamus development
GO:0021860 IEA pyramidal neuron development
GO:0022028 IEA tangential migration from the subventricular zone to the olfactory bulb
GO:0030976 IEA thiamine pyrophosphate binding
GO:0031072 IEA heat shock protein binding
GO:0031966 ISS mitochondrial membrane
GO:0034602 IEA oxoglutarate dehydrogenase (NAD+) activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045252 IEA oxoglutarate dehydrogenase complex
GO:0046872 IEA metal ion binding
GO:0051087 IEA chaperone binding
GO:0055114 IEA oxidation-reduction process
GO:0061034 IEA olfactory bulb mitral cell layer development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034270 ogdha protein_coding Danio_rerio
ENSMUSG00000020456 Ogdh protein_coding Mus_musculus

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