ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: aryl hydrocarbon receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106546 AHR 9606 + 7:17298622-17346152 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000242057 AHR-002 17298622-17346150 protein_coding
  ENST00000463496 AHR-001 17298683-17346152 nonsense_mediated_decay
  ENST00000475440 AHR-003 17329858-17333950 processed_transcript
  ENST00000481944 AHR-004 17334910-17336075 processed_transcript
  ENST00000492120 AHR-005 17335645-17339527 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000242057ENST00000463496ENST00000492120
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000242057 2.399±0.56 8.388±5.91 3.713±0.00 4.783±3.02
ENST00000463496 0.962±0.00 4.538±2.53 1.721±0.00 1.671±0.64
ENST00000492120 N/A 7.638±0.00 N/A 7.055±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001568 NAS blood vessel development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 TAS transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006805 TAS xenobiotic metabolic process
GO:0006915 TAS apoptotic process
GO:0007049 IEA cell cycle
GO:0007165 IEA signal transduction
GO:0008134 IPI transcription factor binding
GO:0009410 IDA response to xenobiotic stimulus
GO:0009636 IDA response to toxic substance
GO:0010468 IDA regulation of gene expression
GO:0030522 IDA intracellular receptor signaling pathway
GO:0030850 IEA prostate gland development
GO:0030888 IDA regulation of B cell proliferation
GO:0032922 ISS circadian regulation of gene expression
GO:0034752 TAS cytosolic aryl hydrocarbon receptor complex
GO:0035326 IDA enhancer binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045899 IEA positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0046982 TAS protein heterodimerization activity
GO:0046983 TAS:IEA protein dimerization activity
GO:0048608 IEA reproductive structure development
GO:0048732 IEA gland development
GO:0051879 IDA Hsp90 protein binding
GO:0070888 ISS E-box binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020046 ahr1a protein_coding Danio_rerio
ENSMUSG00000019256 Ahr protein_coding Mus_musculus

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