ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: leucine zipper, putative tumor suppressor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107816 LZTS2 9606 + 10:100996618-101007836 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370220 LZTS2-001 100999476-101007836 protein_coding
  ENST00000370223 LZTS2-002 100997072-101007836 protein_coding
  ENST00000426584 LZTS2-004 100996618-101003818 protein_coding
  ENST00000429732 LZTS2-007 100998348-101003694 protein_coding
  ENST00000454422 LZTS2-006 100999853-101003760 protein_coding
  ENST00000481129 LZTS2-008 100998687-101002946 protein_coding
  ENST00000489526 LZTS2-005 100997114-101003177 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000370220ENST00000370223ENST00000426584ENST00000454422
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000370220 N/A 0.822±0.02 N/A 1.733±1.17
ENST00000370223 8.695±0.00 3.745±1.65 8.095±0.00 11.195±12.33
ENST00000426584 N/A N/A N/A 0.790±0.00
ENST00000454422 N/A N/A N/A 25.452±20.83

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008BD CIL_0008BD_0001 VISTA
CIL_0007U1 CIL_0007U1_0001 VISTA
CIL_000940 CIL_000940_0001 VISTA
CIL_0005ND CIL_0005ND_0001 CGP
CIL_0001C9 CIL_0001C9_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000910 IEA cytokinesis
GO:0001822 IEA kidney development
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005813 IEA centrosome
GO:0005874 IEA microtubule
GO:0007067 IEA mitotic nuclear division
GO:0008285 IEA negative regulation of cell proliferation
GO:0016055 IEA Wnt signaling pathway
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0030496 IEA midbody
GO:0051013 IEA microtubule severing
GO:0051168 IEA nuclear export
GO:0051255 IEA spindle midzone assembly
GO:0072001 IEA renal system development
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:1900181 IEA negative regulation of protein localization to nucleus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074597 lzts2a protein_coding Danio_rerio
ENSDARG00000077207 lzts2b protein_coding Danio_rerio
ENSMUSG00000035342 Lzts2 protein_coding Mus_musculus

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