ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin specific peptidase 46
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109189 USP46 9606 - 4:52590972-52659335 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000441222 USP46-001 52590972-52659335 protein_coding
  ENST00000451218 USP46-003 52594178-52659290 protein_coding
  ENST00000502443 USP46-009 52626093-52628366 retained_intron
  ENST00000503060 USP46-004 52596814-52659275 nonsense_mediated_decay
  ENST00000504078 USP46-006 52631109-52656586 processed_transcript
  ENST00000506707 USP46-007 52626128-52656573 processed_transcript
  ENST00000508499 USP46-005 52597581-52656590 protein_coding
  ENST00000512656 USP46-008 52628061-52656526 nonsense_mediated_decay
  ENST00000514536 USP46-002 52597467-52659298 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000441222ENST00000451218ENST00000503060ENST00000504078ENST00000508499ENST00000514536
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000441222 0.089±0.00 0.506±0.24 N/A N/A 0.909±0.48
ENST00000451218 0.697±0.48 3.125±0.90 0.255±0.00 4.994±0.00 4.754±4.24
ENST00000503060 N/A N/A N/A N/A 1.277±0.00
ENST00000504078 0.619±0.00 N/A N/A N/A N/A
ENST00000508499 N/A N/A N/A N/A 1.739±0.00
ENST00000514536 N/A 1.169±0.01 N/A N/A 2.598±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001CQ CIL_0001CQ_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 IEA behavioral fear response
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008343 IEA adult feeding behavior
GO:0016579 IDA protein deubiquitination
GO:0032228 ISS regulation of synaptic transmission, GABAergic
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0048149 IEA behavioral response to ethanol
GO:0060013 IEA righting reflex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045343 usp46 protein_coding Danio_rerio
ENSMUSG00000054814 Usp46 protein_coding Mus_musculus

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