ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: deltex 4, E3 ubiquitin ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110042 DTX4 9606 + 11:59171430-59208587 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227451 DTX4-001 59172492-59208587 protein_coding
  ENST00000527475 DTX4-003 59194892-59204758 retained_intron
  ENST00000531902 DTX4-004 59185260-59192251 processed_transcript
  ENST00000532982 DTX4-002 59171430-59204909 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000227451ENST00000531902ENST00000532982
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000227451 0.257±0.25 3.719±0.00 0.085±0.07
ENST00000531902 N/A N/A 0.105±0.00
ENST00000532982 N/A N/A 0.058±0.04

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005829 TAS cytosol
GO:0007219 IEA Notch signaling pathway
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0032479 TAS regulation of type I interferon production
GO:0032481 TAS positive regulation of type I interferon production
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076302 dtx1 protein_coding Danio_rerio
ENSDARG00000078016 dtx4 protein_coding Danio_rerio
ENSMUSG00000039982 Dtx4 protein_coding Mus_musculus

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