ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110717 NDUFS8 9606 + 11:68030617-68036644 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313468 NDUFS8-001 68030627-68036644 protein_coding
  ENST00000432321 NDUFS8-002 68030617-68033730 retained_intron
  ENST00000453471 NDUFS8-011 68030665-68033284 protein_coding
  ENST00000524810 NDUFS8-007 68033141-68036644 nonsense_mediated_decay
  ENST00000525419 NDUFS8-013 68030760-68036348 protein_coding
  ENST00000525628 NDUFS8-014 68030966-68033241 protein_coding
  ENST00000526339 NDUFS8-015 68030743-68036514 protein_coding
  ENST00000526446 NDUFS8-008 68030684-68036537 nonsense_mediated_decay
  ENST00000526542 NDUFS8-006 68033852-68036301 processed_transcript
  ENST00000528492 NDUFS8-004 68030688-68036639 protein_coding
  ENST00000529645 NDUFS8-009 68032161-68035683 nonsense_mediated_decay
  ENST00000531228 NDUFS8-012 68030743-68033223 nonsense_mediated_decay
  ENST00000531282 NDUFS8-010 68036029-68036644 retained_intron
  ENST00000531796 NDUFS8-005 68030653-68032685 retained_intron
  ENST00000532399 NDUFS8-003 68030713-68035278 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000313468ENST00000528492ENST00000532399
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000313468 382.136±130.90 57.155±20.25 43.658±0.00 70.871±0.00 74.491±75.73
ENST00000528492 N/A 87.994±15.20 84.128±0.00 N/A 52.634±23.10
ENST00000532399 N/A 0.500±0.06 2.221±0.00 N/A 1.360±1.14

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003954 IMP NADH dehydrogenase activity
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0005747 IMP mitochondrial respiratory chain complex I
GO:0006120 NAS mitochondrial electron transport, NADH to ubiquinone
GO:0006979 IDA response to oxidative stress
GO:0008137 NAS NADH dehydrogenase (ubiquinone) activity
GO:0016020 IEA membrane
GO:0016651 IEA oxidoreductase activity, acting on NAD(P)H
GO:0022904 TAS respiratory electron transport chain
GO:0032981 IMP mitochondrial respiratory chain complex I assembly
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051986 ndufs8a protein_coding Danio_rerio
ENSDARG00000057055 ndufs8b polymorphic_pseudogene Danio_rerio
ENSMUSG00000059734 Ndufs8 protein_coding Mus_musculus

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