ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111725 PRKAB1 9606 + 12:119667753-119681630 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229328 PRKAB1-001 119667753-119681630 protein_coding
  ENST00000537057 PRKAB1-004 119680078-119681587 processed_transcript
  ENST00000537400 PRKAB1-007 119668150-119672427 nonsense_mediated_decay
  ENST00000538271 PRKAB1-009 119678985-119679981 retained_intron
  ENST00000540121 PRKAB1-005 119669424-119680841 protein_coding
  ENST00000541640 PRKAB1-002 119667864-119681624 protein_coding
  ENST00000542698 PRKAB1-003 119677355-119681619 retained_intron
  ENST00000545223 PRKAB1-006 119672244-119679951 protein_coding
  ENST00000545870 PRKAB1-008 119673810-119680001 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000229328ENST00000537057ENST00000540121ENST00000541640ENST00000542698
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000229328 2.957±0.00 2.902±1.04 N/A 7.532±0.00 6.626±4.16
ENST00000537057 10.213±0.18 2.444±0.00 16.473±0.00 N/A N/A
ENST00000540121 N/A N/A N/A N/A 0.843±0.02
ENST00000541640 N/A 3.984±0.92 N/A 2.786±0.00 2.317±1.41
ENST00000542698 N/A 0.701±0.17 1.583±0.00 N/A 1.132±0.69

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007G8 CIL_0007G8_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004679 IEA AMP-activated protein kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006468 IDA protein phosphorylation
GO:0006633 IEA fatty acid biosynthetic process
GO:0007050 TAS cell cycle arrest
GO:0007165 TAS signal transduction
GO:0008286 TAS insulin receptor signaling pathway
GO:0010628 IDA positive regulation of gene expression
GO:0019901 IEA protein kinase binding
GO:0031588 IEA AMP-activated protein kinase complex
GO:0043234 IEA protein complex
GO:0050790 IEA regulation of catalytic activity
GO:0051291 IEA protein heterooligomerization
GO:0061024 TAS membrane organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044183 prkab1a protein_coding Danio_rerio
ENSDARG00000046143 prkab1b protein_coding Danio_rerio
ENSMUSG00000029513 Prkab1 protein_coding Mus_musculus

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