ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein tyrosine kinase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112655 PTK7 9606 + 6:43076268-43161719 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230418 PTK7-007 43076342-43161712 nonsense_mediated_decay
  ENST00000230419 PTK7-001 43076268-43161719 protein_coding
  ENST00000345201 PTK7-006 43076342-43161712 protein_coding
  ENST00000349241 PTK7-004 43076342-43161712 protein_coding
  ENST00000352931 PTK7-005 43076342-43161712 protein_coding
  ENST00000461100 PTK7-019 43142377-43145259 nonsense_mediated_decay
  ENST00000461389 PTK7-021 43144300-43161036 nonsense_mediated_decay
  ENST00000470019 PTK7-002 43076333-43161719 nonsense_mediated_decay
  ENST00000470471 PTK7-016 43138553-43141948 retained_intron
  ENST00000471863 PTK7-003 43076339-43133721 protein_coding
  ENST00000473339 PTK7-020 43144299-43159883 protein_coding
  ENST00000476760 PTK7-013 43076307-43129617 protein_coding
  ENST00000481273 PTK7-009 43076814-43161010 protein_coding
  ENST00000481946 PTK7-015 43130591-43139243 protein_coding
  ENST00000487673 PTK7-008 43076369-43161713 retained_intron
  ENST00000489707 PTK7-012 43132526-43161719 protein_coding
  ENST00000490710 PTK7-014 43131714-43132551 retained_intron
  ENST00000493339 PTK7-011 43142348-43146164 retained_intron
  ENST00000494146 PTK7-018 43142377-43145261 nonsense_mediated_decay
  ENST00000497957 PTK7-017 43142379-43145432 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000230418ENST00000230419ENST00000345201ENST00000349241ENST00000352931ENST00000470019ENST00000471863ENST00000481273ENST00000487673ENST00000489707
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000230418 N/A 5.316±2.83 N/A 2.920±3.09
ENST00000230419 0.841±0.00 6.281±5.20 4.723±0.00 6.858±6.68
ENST00000345201 N/A 1.575±0.00 N/A 1.037±0.00
ENST00000349241 0.888±0.00 N/A 1.403±0.00 N/A
ENST00000352931 N/A 2.906±2.03 N/A 3.682±2.96
ENST00000470019 N/A 3.452±2.01 1.624±0.00 0.591±0.05
ENST00000471863 N/A 0.143±0.05 N/A N/A
ENST00000481273 N/A 3.189±3.18 N/A 2.551±1.66
ENST00000487673 N/A 0.042±0.00 N/A 2.377±2.91
ENST00000489707 1.813±0.00 8.391±4.46 3.746±0.00 6.611±5.23

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001736 IEA establishment of planar polarity
GO:0001843 IEA neural tube closure
GO:0003401 IEA axis elongation
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0007155 IEA cell adhesion
GO:0007165 TAS signal transduction
GO:0010976 IMP positive regulation of neuron projection development
GO:0016020 IEA membrane
GO:0016477 IMP cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0031532 IMP actin cytoskeleton reorganization
GO:0042060 IEA wound healing
GO:0045198 IEA establishment of epithelial cell apical/basal polarity
GO:0060026 IEA convergent extension
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060484 IEA lung-associated mesenchyme development
GO:0071300 IMP cellular response to retinoic acid
GO:0090103 IEA cochlea morphogenesis
GO:0090179 IEA planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011863 ptk7a protein_coding Danio_rerio
ENSMUSG00000023972 Ptk7 protein_coding Mus_musculus

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