ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: laminin, alpha 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112769 LAMA4 9606 - 6:112108760-112254939 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230538 LAMA4-001 112108760-112254715 protein_coding
  ENST00000243219 LAMA4-016 112216402-112254538 protein_coding
  ENST00000368638 LAMA4-005 112253361-112254588 protein_coding
  ENST00000368640 LAMA4-003 112179766-112191764 protein_coding
  ENST00000389463 LAMA4-009 112108874-112254600 protein_coding
  ENST00000423735 LAMA4-004 112200133-112216449 processed_transcript
  ENST00000424408 LAMA4-012 112109293-112254538 protein_coding
  ENST00000431543 LAMA4-002 112213543-112254572 protein_coding
  ENST00000453937 LAMA4-010 112253784-112254578 protein_coding
  ENST00000455073 LAMA4-006 112253790-112254647 protein_coding
  ENST00000518842 LAMA4-018 112188892-112191801 retained_intron
  ENST00000519245 LAMA4-020 112135825-112139276 retained_intron
  ENST00000519932 LAMA4-015 112207123-112254722 protein_coding
  ENST00000521187 LAMA4-013 112171630-112179502 retained_intron
  ENST00000521398 LAMA4-011 112185319-112254485 protein_coding
  ENST00000521690 LAMA4-014 112216421-112254939 protein_coding
  ENST00000521693 LAMA4-021 112122061-112130159 retained_intron
  ENST00000521732 LAMA4-007 112179735-112191811 protein_coding
  ENST00000522006 LAMA4-008 112108860-112254710 protein_coding
  ENST00000523765 LAMA4-019 112142144-112165164 nonsense_mediated_decay
  ENST00000524032 LAMA4-017 112191719-112216754 processed_transcript
  ENST00000604740 LAMA4-022 112121775-112129988 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000230538ENST00000389463ENST00000424408ENST00000453937ENST00000455073ENST00000522006
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000230538 21.911±0.00 10.917±6.55 N/A N/A 31.124±15.24
ENST00000389463 57.143±0.00 29.835±14.93 N/A 103.701±0.00 55.858±35.15
ENST00000424408 N/A 11.696±7.88 N/A 46.623±0.00 28.312±11.67
ENST00000453937 177.881±0.00 N/A N/A N/A 71.649±0.00
ENST00000455073 167.518±0.00 N/A N/A N/A N/A
ENST00000522006 N/A 15.550±4.27 6.534±0.00 N/A 28.541±20.78

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IEA blood vessel development
GO:0004713 IEA protein tyrosine kinase activity
GO:0004871 IEA signal transducer activity
GO:0005102 IEA receptor binding
GO:0005201 TAS extracellular matrix structural constituent
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005604 IEA basement membrane
GO:0005605 IEA basal lamina
GO:0005606 IEA laminin-1 complex
GO:0005925 IEA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0007155 IEA cell adhesion
GO:0007172 IEA signal complex assembly
GO:0030155 IEA regulation of cell adhesion
GO:0030198 TAS extracellular matrix organization
GO:0030334 IEA regulation of cell migration
GO:0031012 ISS extracellular matrix
GO:0045995 IEA regulation of embryonic development
GO:0050873 IEA brown fat cell differentiation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020785 lama4 protein_coding Danio_rerio
ENSMUSG00000019846 Lama4 protein_coding Mus_musculus

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