ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: CDC-like kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113240 CLK4 9606 - 5:178602664-178630615 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316308 CLK4-001 178602664-178627114 protein_coding
  ENST00000519132 CLK4-008 178603270-178617388 retained_intron
  ENST00000519583 CLK4-013 178603272-178627041 retained_intron
  ENST00000520126 CLK4-007 178617731-178627052 retained_intron
  ENST00000520199 CLK4-006 178617071-178627054 retained_intron
  ENST00000520878 CLK4-005 178602664-178627088 retained_intron
  ENST00000520909 CLK4-002 178617697-178630615 retained_intron
  ENST00000520957 CLK4-012 178621812-178627030 protein_coding
  ENST00000521621 CLK4-003 178603270-178627029 nonsense_mediated_decay
  ENST00000522136 CLK4-009 178603168-178627055 nonsense_mediated_decay
  ENST00000522556 CLK4-004 178618694-178627112 nonsense_mediated_decay
  ENST00000522749 CLK4-011 178616882-178620119 processed_transcript
  ENST00000523013 CLK4-010 178621809-178623339 retained_intron
  ENST00000611575 CLK4-201 178603589-178627001 protein_coding
  ENST00000611733 CLK4-202 178602665-178627053 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000316308ENST00000519132ENST00000519583ENST00000520199ENST00000520878ENST00000520957ENST00000521621ENST00000522136ENST00000522556ENST00000611575ENST00000611733
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000316308 1.656±0.00 0.593±0.21 12.612±0.00 2.788±0.00 1.581±1.14
ENST00000519132 N/A 0.144±0.06 N/A N/A 0.439±0.00
ENST00000519583 N/A 0.604±0.41 N/A 1.383±0.00 1.466±1.29
ENST00000520199 N/A N/A N/A N/A 2.746±0.33
ENST00000520878 N/A 0.128±0.00 N/A N/A 0.678±0.22
ENST00000520957 N/A N/A N/A N/A 1.222±0.00
ENST00000521621 N/A N/A N/A N/A 1.909±1.27
ENST00000522136 N/A 0.499±0.16 N/A N/A 1.532±0.74
ENST00000522556 N/A N/A N/A N/A 2.037±0.35
ENST00000611575 N/A 0.968±0.17 N/A 2.031±0.00 3.494±0.59
ENST00000611733 2.656±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000XD CIL_0000XD_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0006468 IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0043484 IMP regulation of RNA splicing
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005908 clk4b protein_coding Danio_rerio
ENSDARG00000089372 clk4a protein_coding Danio_rerio
ENSMUSG00000020385 Clk4 protein_coding Mus_musculus

Loading