ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: chloride channel, voltage-sensitive 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114859 CLCN2 9606 - 3:184346185-184361651 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265593 CLCN2-001 184346185-184361651 protein_coding
  ENST00000344937 CLCN2-004 184346188-184361602 protein_coding
  ENST00000430397 CLCN2-006 184346221-184357020 nonsense_mediated_decay
  ENST00000434054 CLCN2-003 184346398-184361603 protein_coding
  ENST00000457512 CLCN2-002 184346520-184361603 protein_coding
  ENST00000465231 CLCN2-009 184357972-184358658 retained_intron
  ENST00000475279 CLCN2-007 184355403-184357029 processed_transcript
  ENST00000485667 CLCN2-005 184355055-184361486 retained_intron
  ENST00000491162 CLCN2-008 184352416-184353296 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000265593ENST00000344937ENST00000430397ENST00000434054
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000265593 N/A 3.402±2.01 N/A 1.849±0.59
ENST00000344937 N/A 3.590±1.07 N/A N/A
ENST00000430397 2.454±0.13 N/A 4.819±0.00 N/A
ENST00000434054 N/A 4.410±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005G3 CIL_0005G3_0001 CGP
CIL_00056Z CIL_00056Z_0001 CGP
CIL_000570 CIL_000570_0001 CGP
CIL_00056X CIL_00056X_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005247 IEA voltage-gated chloride channel activity
GO:0005886 TAS plasma membrane
GO:0006810 TAS transport
GO:0006821 IEA chloride transport
GO:0016020 IEA membrane
GO:0030554 IEA adenyl nucleotide binding
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0044070 IEA regulation of anion transport
GO:0055085 TAS:IEA transmembrane transport
GO:0060041 IEA retina development in camera-type eye
GO:0060689 IEA cell differentiation involved in salivary gland development
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060439 si:ch211-229n1.3 protein_coding Danio_rerio
ENSDARG00000062427 clcn2 protein_coding Danio_rerio
ENSMUSG00000022843 Clcn2 protein_coding Mus_musculus

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