ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: four and a half LIM domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115641 FHL2 9606 - 2:105357712-105438513 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322142 FHL2-004 105360828-105399061 protein_coding
  ENST00000344213 FHL2-002 105360812-105399224 protein_coding
  ENST00000358129 FHL2-201 105360828-105399224 protein_coding
  ENST00000393352 FHL2-009 105360826-105438503 protein_coding
  ENST00000393353 FHL2-003 105360826-105399051 protein_coding
  ENST00000408995 FHL2-005 105360861-105399050 protein_coding
  ENST00000409177 FHL2-006 105357712-105399667 protein_coding
  ENST00000409807 FHL2-001 105360857-105396957 protein_coding
  ENST00000447958 FHL2-007 105386458-105396785 protein_coding
  ENST00000452732 FHL2-008 105363284-105396697 nonsense_mediated_decay
  ENST00000530340 FHL2-010 105360826-105399224 nonsense_mediated_decay
  ENST00000607522 FHL2-011 105385897-105438513 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000322142ENST00000344213ENST00000393352ENST00000393353ENST00000408995ENST00000409177ENST00000409807ENST00000530340
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000322142 14.331±3.44 23.668±14.63 N/A 12.329±0.00 34.695±25.07
ENST00000344213 N/A 3.840±0.00 N/A N/A 15.042±9.20
ENST00000393352 31.724±0.00 18.332±12.23 N/A N/A N/A
ENST00000393353 19.986±12.97 18.488±13.20 N/A 29.847±0.00 49.998±23.59
ENST00000408995 54.555±0.00 13.960±7.85 1.376±0.00 19.171±0.00 43.211±28.45
ENST00000409177 N/A 1.322±0.00 N/A N/A 3.263±0.28
ENST00000409807 N/A N/A N/A N/A 17.546±4.80
ENST00000530340 N/A N/A 0.893±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00096O CIL_00096O_0001 VISTA
CIL_00010E CIL_00010E_0001 CGP
CIL_00010G CIL_00010G_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001649 IEA osteoblast differentiation
GO:0003713 NAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005925 IDA focal adhesion
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0009725 IMP response to hormone
GO:0015629 IDA actin cytoskeleton
GO:0030018 IEA Z disc
GO:0030521 NAS androgen receptor signaling pathway
GO:0031430 IEA M band
GO:0042802 IPI identical protein binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0050681 NAS androgen receptor binding
GO:0055014 IEA atrial cardiac muscle cell development
GO:0055015 IEA ventricular cardiac muscle cell development
GO:0060347 IEA heart trabecula formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003991 fhl2b protein_coding Danio_rerio
ENSDARG00000042018 fhl2a protein_coding Danio_rerio
ENSMUSG00000008136 Fhl2 protein_coding Mus_musculus

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