ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115657 ABCB6 9606 - 2:219209768-219218990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265316 ABCB6-001 219209768-219218990 protein_coding
  ENST00000295750 ABCB6-005 219209772-219218354 protein_coding
  ENST00000417678 ABCB6-003 219214168-219218426 nonsense_mediated_decay
  ENST00000443805 ABCB6-012 219209776-219211038 nonsense_mediated_decay
  ENST00000448398 ABCB6-015 219213240-219218476 nonsense_mediated_decay
  ENST00000452545 ABCB6-007 219215029-219218190 nonsense_mediated_decay
  ENST00000485773 ABCB6-013 219209772-219211108 retained_intron
  ENST00000487380 ABCB6-014 219209772-219211039 retained_intron
  ENST00000492543 ABCB6-011 219210711-219213420 retained_intron
  ENST00000492953 ABCB6-008 219214141-219216288 retained_intron
  ENST00000494639 ABCB6-010 219213602-219214683 retained_intron
  ENST00000496984 ABCB6-009 219213898-219215437 retained_intron
  ENST00000497882 ABCB6-006 219209772-219215885 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000265316ENST00000295750ENST00000443805ENST00000497882
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000265316 N/A 5.315±1.08 N/A 10.009±2.59
ENST00000295750 N/A 13.331±0.00 N/A N/A
ENST00000443805 82.069±0.00 N/A 19.990±0.00 N/A
ENST00000497882 N/A N/A N/A 7.148±0.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000916 CIL_000916_0001 VISTA
CIL_0006EB CIL_0006EB_0001 CGP
CIL_0006EA CIL_0006EA_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005524 IDA:IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005740 IDA mitochondrial envelope
GO:0005741 IDA mitochondrial outer membrane
GO:0005768 ISS endosome
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006779 IDA porphyrin-containing compound biosynthetic process
GO:0006810 IDA:IEA transport
GO:0006879 NAS cellular iron ion homeostasis
GO:0007420 IMP brain development
GO:0015232 TAS heme transporter activity
GO:0015439 IMP heme-transporting ATPase activity
GO:0015562 IDA efflux transmembrane transporter activity
GO:0015886 IMP heme transport
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0020037 IDA heme binding
GO:0031307 IDA integral component of mitochondrial outer membrane
GO:0042626 IEA ATPase activity, coupled to transmembrane movement of substances
GO:0043190 NAS ATP-binding cassette (ABC) transporter complex
GO:0043588 IMP skin development
GO:0055085 IBA:IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063297 abcb6a protein_coding Danio_rerio
ENSDARG00000074254 abcb6b protein_coding Danio_rerio
ENSMUSG00000026198 Abcb6 protein_coding Mus_musculus

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