ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: transmembrane protein 59
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116209 TMEM59 9606 - 1:54031663-54053504 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000234831 TMEM59-001 54031676-54053438 protein_coding
  ENST00000371337 TMEM59-004 54045486-54053192 protein_coding
  ENST00000371341 TMEM59-005 54031966-54053504 protein_coding
  ENST00000371344 TMEM59-003 54031676-54044942 protein_coding
  ENST00000371348 TMEM59-002 54031663-54048013 protein_coding
  ENST00000420738 TMEM59-007 54036599-54053412 protein_coding
  ENST00000440019 TMEM59-006 54036599-54053441 protein_coding
  ENST00000452421 TMEM59-008 54036602-54053405 protein_coding
  ENST00000470395 TMEM59-009 54032019-54036802 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000234831ENST00000371337ENST00000371341ENST00000371344ENST00000371348ENST00000420738ENST00000440019ENST00000470395
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000234831 26.082±16.37 44.120±14.01 N/A 48.228±0.00 49.086±37.29
ENST00000371337 N/A N/A N/A N/A 21.982±4.94
ENST00000371341 N/A 15.075±2.62 N/A N/A 12.612±8.42
ENST00000371344 N/A N/A N/A N/A 0.372±0.00
ENST00000371348 N/A N/A N/A N/A 2.264±0.00
ENST00000420738 N/A 45.682±2.64 N/A N/A 32.915±19.27
ENST00000440019 34.689±0.00 55.018±1.23 N/A 71.012±0.00 84.644±0.00
ENST00000470395 133.784±15.32 41.956±0.05 67.982±0.00 74.957±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000137 IDA Golgi cis cisterna
GO:0000138 IDA Golgi trans cisterna
GO:0004175 IEA endopeptidase activity
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005770 IDA late endosome
GO:0005797 IDA Golgi medial cisterna
GO:0005886 IEA plasma membrane
GO:0006508 IEA proteolysis
GO:0006914 IEA autophagy
GO:0010508 IMP positive regulation of autophagy
GO:0010955 IDA negative regulation of protein processing
GO:0016021 IEA integral component of membrane
GO:0070062 IDA extracellular vesicular exosome
GO:0090005 IDA negative regulation of establishment of protein localization to plasma membrane
GO:0090285 IDA negative regulation of protein glycosylation in Golgi

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019033 tmem59 protein_coding Danio_rerio
ENSMUSG00000028618 Tmem59 protein_coding Mus_musculus

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