ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ash1 (absent, small, or homeotic)-like (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116539 ASH1L 9606 - 1:155335268-155562807 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368346 ASH1L-001 155335268-155562693 protein_coding
  ENST00000392403 ASH1L-002 155336055-155562532 protein_coding
  ENST00000477427 ASH1L-005 155370147-155370868 retained_intron
  ENST00000478837 ASH1L-003 155343041-155346429 retained_intron
  ENST00000492987 ASH1L-004 155343656-155349351 nonsense_mediated_decay
  ENST00000548566 ASH1L-007 155343451-155344591 retained_intron
  ENST00000548830 ASH1L-006 155481411-155562807 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000368346ENST00000392403
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000368346 0.744±0.45 0.292±0.00 N/A 1.523±0.75
ENST00000392403 2.386±3.12 N/A 2.030±0.00 2.312±1.47

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002674 IEA negative regulation of acute inflammatory response
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0005515 IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005694 IEA chromosome
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005923 IEA tight junction
GO:0006323 TAS DNA packaging
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007267 TAS cell-cell signaling
GO:0008270 IEA zinc ion binding
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0032635 IEA interleukin-6 production
GO:0034968 IEA histone lysine methylation
GO:0042800 IEA histone methyltransferase activity (H3-K4 specific)
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043409 IEA negative regulation of MAPK cascade
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050728 IEA negative regulation of inflammatory response
GO:0051568 IEA histone H3-K4 methylation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070981 ash1l protein_coding Danio_rerio
ENSMUSG00000028053 Ash1l protein_coding Mus_musculus

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