ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: leptin receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116678 LEPR 9606 + 1:65420652-65641559 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344610 LEPR-201 65525689-65626234 protein_coding
  ENST00000349533 LEPR-001 65420652-65641559 protein_coding
  ENST00000371058 LEPR-005 65565546-65626234 protein_coding
  ENST00000371059 LEPR-003 65420652-65630422 protein_coding
  ENST00000371060 LEPR-002 65420652-65635428 protein_coding
  ENST00000406510 LEPR-202 65420720-65637102 protein_coding
  ENST00000462765 LEPR-004 65525689-65610268 processed_transcript
  ENST00000471762 LEPR-006 65619940-65623384 processed_transcript
  ENST00000616738 LEPR-203 65525689-65635409 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000371058ENST00000371060ENST00000462765ENST00000616738
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000371058 N/A N/A 5.484±0.00
ENST00000371060 2.301±0.00 N/A N/A
ENST00000462765 N/A N/A 8.375±1.17
ENST00000616738 N/A 23.235±0.00 12.496±15.12

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000267 CIL_000267_0001 CGP
CIL_000264 CIL_000264_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004888 TAS transmembrane signaling receptor activity
GO:0004896 IEA cytokine receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0008203 IEA cholesterol metabolic process
GO:0016021 IEA integral component of membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0042802 IPI identical protein binding
GO:0043235 IDA receptor complex
GO:0045721 IEA negative regulation of gluconeogenesis
GO:0051346 IEA negative regulation of hydrolase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070961 lepr protein_coding Danio_rerio
ENSMUSG00000057722 Lepr protein_coding Mus_musculus

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