ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: aldo-keto reductase family 1, member A1 (aldehyde reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117448 AKR1A1 9606 + 1:45550543-45570049 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000351829 AKR1A1-002 45551067-45570049 protein_coding
  ENST00000372070 AKR1A1-001 45550543-45570049 protein_coding
  ENST00000434299 AKR1A1-004 45550804-45568068 protein_coding
  ENST00000471651 AKR1A1-007 45551068-45567588 protein_coding
  ENST00000473038 AKR1A1-003 45567549-45570049 processed_transcript
  ENST00000475919 AKR1A1-009 45568614-45570047 processed_transcript
  ENST00000475985 AKR1A1-010 45569050-45570045 processed_transcript
  ENST00000476957 AKR1A1-006 45550854-45568624 processed_transcript
  ENST00000481885 AKR1A1-011 45551067-45568025 protein_coding
  ENST00000487654 AKR1A1-013 45568147-45570044 processed_transcript
  ENST00000495913 AKR1A1-008 45567982-45570049 processed_transcript
  ENST00000496999 AKR1A1-005 45550846-45567213 processed_transcript
  ENST00000497973 AKR1A1-012 45566869-45570049 processed_transcript
  ENST00000621846 AKR1A1-201 45550783-45570048 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000351829ENST00000372070ENST00000434299ENST00000471651ENST00000473038ENST00000476957ENST00000481885ENST00000487654ENST00000495913ENST00000621846
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000351829 34.812±16.27 24.938±8.15 N/A 32.569±0.00 40.212±22.90
ENST00000372070 N/A N/A N/A N/A 6.493±4.42
ENST00000434299 N/A 20.009±5.46 N/A N/A 24.766±12.02
ENST00000471651 N/A N/A 13.644±0.00 N/A 6.235±5.73
ENST00000473038 N/A N/A 19.041±0.00 N/A 6.497±5.86
ENST00000476957 N/A 15.326±2.43 N/A 20.941±0.00 5.518±4.57
ENST00000481885 N/A 35.841±4.31 N/A N/A 47.371±36.59
ENST00000487654 69.478±3.75 30.901±3.46 43.914±0.00 N/A N/A
ENST00000495913 161.673±21.01 74.409±9.59 83.931±0.00 63.721±0.00 N/A
ENST00000621846 N/A 5.077±0.36 N/A N/A 24.735±18.81

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004032 TAS alditol:NADP+ 1-oxidoreductase activity
GO:0005615 IDA extracellular space
GO:0005829 IEA cytosol
GO:0006006 TAS glucose metabolic process
GO:0006081 TAS cellular aldehyde metabolic process
GO:0009055 TAS electron carrier activity
GO:0016324 IEA apical plasma membrane
GO:0016491 IEA oxidoreductase activity
GO:0019853 IEA L-ascorbic acid biosynthetic process
GO:0042840 IEA D-glucuronate catabolic process
GO:0046185 IEA aldehyde catabolic process
GO:0047939 IEA L-glucuronate reductase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052030 akr1a1b protein_coding Danio_rerio
ENSMUSG00000028692 Akr1a1 protein_coding Mus_musculus

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