ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: peroxiredoxin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117450 PRDX1 9606 - 1:45511036-45523047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262746 PRDX1-201 45511036-45521938 protein_coding
  ENST00000319248 PRDX1-001 45511047-45521956 protein_coding
  ENST00000372079 PRDX1-003 45511051-45521854 protein_coding
  ENST00000424390 PRDX1-004 45514507-45523047 protein_coding
  ENST00000447184 PRDX1-002 45514507-45521938 protein_coding
  ENST00000483583 PRDX1-005 45515654-45521867 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262746ENST00000319248ENST00000372079ENST00000424390ENST00000447184
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262746 N/A N/A N/A N/A 0.765±0.00
ENST00000319248 498.460±135.05 594.821±325.43 64.355±0.00 287.724±0.00 330.222±216.22
ENST00000372079 725.548±161.43 238.703±112.62 253.844±0.00 N/A 72.980±0.00
ENST00000424390 N/A N/A N/A N/A 5.588±0.00
ENST00000447184 N/A 166.635±40.86 N/A 204.626±0.00 126.218±10.09

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000302 IEA response to reactive oxygen species
GO:0001501 TAS skeletal system development
GO:0001895 IEP retina homeostasis
GO:0004601 IDA peroxidase activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005719 IEA nuclear euchromatin
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005759 IEA mitochondrial matrix
GO:0005782 IEA peroxisomal matrix
GO:0005829 TAS cytosol
GO:0006979 IEA response to oxidative stress
GO:0008283 IEA cell proliferation
GO:0008379 IDA thioredoxin peroxidase activity
GO:0016209 IEA antioxidant activity
GO:0016491 IEA oxidoreductase activity
GO:0019430 IEA removal of superoxide radicals
GO:0020037 IEA heme binding
GO:0032872 IEA regulation of stress-activated MAPK cascade
GO:0034101 IEA erythrocyte homeostasis
GO:0042267 IEA natural killer cell mediated cytotoxicity
GO:0042345 IEA regulation of NF-kappaB import into nucleus
GO:0042744 IDA hydrogen peroxide catabolic process
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0044822 IDA poly(A) RNA binding
GO:0051920 IEA peroxiredoxin activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058734 prdx1 protein_coding Danio_rerio
ENSMUSG00000028691 Prdx1 protein_coding Mus_musculus

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