ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117505 DR1 9606 + 1:93345888-93369498 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370267 DR1-002 93345935-93361168 protein_coding
  ENST00000370272 DR1-001 93345888-93369498 protein_coding
  ENST00000481583 DR1-003 93354975-93360935 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000370267ENST00000370272
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000370267 12.533±3.12 26.148±4.58 N/A 33.713±0.00 18.630±11.64
ENST00000370272 1.352±0.43 4.107±1.38 2.155±0.00 4.352±0.00 3.149±1.53

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005ZW CIL_0005ZW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 TAS DNA binding
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005671 IDA Ada2/Gcn5/Ada3 transcription activator complex
GO:0006325 TAS chromatin organization
GO:0006351 IEA transcription, DNA-templated
GO:0008134 TAS transcription factor binding
GO:0017025 IDA TBP-class protein binding
GO:0043565 IEA sequence-specific DNA binding
GO:0043966 IDA histone H3 acetylation
GO:0046982 IEA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029265 Dr1 protein_coding Mus_musculus

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