ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein phosphatase 1, regulatory subunit 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117751 PPP1R8 9606 + 1:27830778-27851676 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000236412 PPP1R8-003 27830814-27851528 protein_coding
  ENST00000311772 PPP1R8-001 27830778-27851676 protein_coding
  ENST00000373931 PPP1R8-002 27830822-27851672 protein_coding
  ENST00000431586 PPP1R8-005 27831324-27850432 protein_coding
  ENST00000486634 PPP1R8-004 27850093-27851676 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000236412ENST00000311772ENST00000431586
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000236412 N/A N/A N/A N/A 0.437±0.00
ENST00000311772 7.905±1.65 11.953±3.09 4.375±0.00 16.519±0.00 13.027±6.89
ENST00000431586 N/A 9.861±2.85 N/A 9.932±0.00 7.051±3.43

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003723 IEA RNA binding
GO:0004519 IEA endonuclease activity
GO:0004865 TAS protein serine/threonine phosphatase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005681 IEA spliceosomal complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0006401 TAS RNA catabolic process
GO:0008283 IEA cell proliferation
GO:0008380 IEA RNA splicing
GO:0008599 IEA protein phosphatase type 1 regulator activity
GO:0008995 TAS ribonuclease E activity
GO:0016607 IDA nuclear speck
GO:0043086 IEA negative regulation of catalytic activity
GO:0050790 IEA regulation of catalytic activity
GO:0090501 TAS RNA phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007186 ppp1r8a protein_coding Danio_rerio
ENSDARG00000022430 ppp1r8b protein_coding Danio_rerio
ENSMUSG00000028882 Ppp1r8 protein_coding Mus_musculus

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