ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Kruppel-like factor 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118922 KLF12 9606 - 13:73686089-74133905 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377666 KLF12-201 73695490-74133905 protein_coding
  ENST00000377669 KLF12-001 73686089-73995049 protein_coding
  ENST00000472022 KLF12-002 73812873-73995056 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000377666ENST00000377669ENST00000472022
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000377666 N/A 1.532±0.29 N/A N/A 3.099±1.31
ENST00000377669 0.564±0.00 1.210±0.94 0.111±0.00 0.026±0.00 2.417±1.45
ENST00000472022 N/A N/A N/A N/A 14.492±8.86

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00051S CIL_00051S_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015312 klf12a protein_coding Danio_rerio
ENSDARG00000032197 klf12b protein_coding Danio_rerio
ENSMUSG00000072294 Klf12 protein_coding Mus_musculus

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