ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: tight junction protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119139 TJP2 9606 + 9:69121264-69255208 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265384 TJP2-004 69174294-69248990 protein_coding
  ENST00000348208 TJP2-006 69174277-69255204 protein_coding
  ENST00000377245 TJP2-003 69174165-69255204 protein_coding
  ENST00000377259 TJP2-002 69151646-69218539 protein_coding
  ENST00000413932 TJP2-008 69121293-69122232 retained_intron
  ENST00000423935 TJP2-001 69151650-69221096 protein_coding
  ENST00000453658 TJP2-201 69121264-69255208 protein_coding
  ENST00000498204 TJP2-005 69246226-69248089 processed_transcript
  ENST00000535702 TJP2-202 69205011-69255208 protein_coding
  ENST00000539225 TJP2-203 69205162-69255208 protein_coding
  ENST00000606364 TJP2-007 69121308-69221016 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000265384ENST00000377245ENST00000413932ENST00000453658ENST00000539225
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000265384 N/A 7.120±0.94 N/A 5.096±3.41
ENST00000377245 N/A 37.728±9.81 12.211±0.00 17.023±14.48
ENST00000413932 N/A N/A N/A 1.754±0.00
ENST00000453658 5.576±0.00 N/A N/A 4.373±0.00
ENST00000539225 3.933±0.75 13.826±6.75 N/A 14.570±13.75

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004385 TAS guanylate kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005923 IDA tight junction
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008022 IEA protein C-terminus binding
GO:0010033 IEA response to organic substance
GO:0030054 IDA cell junction
GO:0035329 TAS hippo signaling
GO:0046939 TAS nucleotide phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023443 tjp2b protein_coding Danio_rerio
ENSDARG00000063309 tjp2a protein_coding Danio_rerio
ENSMUSG00000024812 Tjp2 protein_coding Mus_musculus

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