ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: msh homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120149 MSX2 9606 + 5:174724533-174730893 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000239243 MSX2-001 174724533-174730893 protein_coding
  ENST00000507785 MSX2-002 174724602-174729880 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000239243ENST00000507785
Transcript ID BECs HAoEC HUVEC
ENST00000239243 0.086±0.00 0.453±0.43 0.050±0.03
ENST00000507785 0.070±0.00 0.692±0.63 0.089±0.08

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00086T CIL_00086T_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000982 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0000989 IEA transcription factor binding transcription factor activity
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001503 IEA ossification
GO:0001649 ISS osteoblast differentiation
GO:0002063 IEA chondrocyte development
GO:0002076 IEA osteoblast development
GO:0003148 IEA outflow tract septum morphogenesis
GO:0003151 IEA outflow tract morphogenesis
GO:0003198 IEA epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003416 IEA endochondral bone growth
GO:0003677 IEA DNA binding
GO:0003712 ISS transcription cofactor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0008134 IEA transcription factor binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0009952 IEA anterior/posterior pattern specification
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030326 IEA embryonic limb morphogenesis
GO:0030509 IEA BMP signaling pathway
GO:0030513 IEA positive regulation of BMP signaling pathway
GO:0032792 IEA negative regulation of CREB transcription factor activity
GO:0035115 IEA embryonic forelimb morphogenesis
GO:0035116 IEA embryonic hindlimb morphogenesis
GO:0035313 IEA wound healing, spreading of epidermal cells
GO:0035880 IEA embryonic nail plate morphogenesis
GO:0042060 IEA wound healing
GO:0042476 IEA odontogenesis
GO:0042733 IEA embryonic digit morphogenesis
GO:0042981 IEA regulation of apoptotic process
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0045617 IEA negative regulation of keratinocyte differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0048863 IEA stem cell differentiation
GO:0051216 IEA cartilage development
GO:0051795 IEA positive regulation of catagen
GO:0060346 IEA bone trabecula formation
GO:0060349 IEA bone morphogenesis
GO:0060363 TAS cranial suture morphogenesis
GO:0060364 IEA frontal suture morphogenesis
GO:0060444 IEA branching involved in mammary gland duct morphogenesis
GO:0061180 IEA mammary gland epithelium development
GO:0061312 IEA BMP signaling pathway involved in heart development
GO:0070166 IEA enamel mineralization
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071392 IEA cellular response to estradiol stimulus
GO:0090427 IEA activation of meiosis
GO:2000678 ISS negative regulation of transcription regulatory region DNA binding
GO:2001055 IEA positive regulation of mesenchymal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008886 msxb protein_coding Danio_rerio
ENSDARG00000015674 msxc protein_coding Danio_rerio
ENSMUSG00000021469 Msx2 protein_coding Mus_musculus

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