ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: islet amyloid polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000121351 IAPP 9606 + 12:21354959-21379978 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000240652 IAPP-001 21372884-21379978 protein_coding
  ENST00000535428 IAPP-004 21373407-21378629 protein_coding
  ENST00000537593 IAPP-003 21372928-21378395 protein_coding
  ENST00000539393 IAPP-005 21354959-21378495 protein_coding
  ENST00000542023 IAPP-002 21372919-21379978 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000240652
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000240652 0.035±0.01 0.030±0.02 0.081±0.00 0.151±0.00 0.083±0.06

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005PW CIL_0005PW_0001 CGP
CIL_0005PZ CIL_0005PZ_0001 CGP
CIL_0006XQ CIL_0006XQ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005179 IEA hormone activity
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006915 TAS apoptotic process
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0019233 IEA sensory perception of pain
GO:0031018 TAS endocrine pancreas development
GO:0042755 IEA eating behavior
GO:0042802 IPI identical protein binding
GO:0043025 IEA neuronal cell body
GO:0045596 IEA negative regulation of cell differentiation
GO:0045779 IEA negative regulation of bone resorption

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000041681 Iapp protein_coding Mus_musculus

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