ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: early growth response 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122877 EGR2 9606 - 10:62811996-62919900 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000242480 EGR2-001 62811996-62816355 protein_coding
  ENST00000411732 EGR2-201 62812003-62816366 protein_coding
  ENST00000439032 EGR2-202 62812003-62819167 protein_coding
  ENST00000493899 EGR2-002 62814433-62919900 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000242480ENST00000411732ENST00000439032
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000242480 N/A 0.199±0.09 0.864±0.00 0.649±1.41
ENST00000411732 0.027±0.00 0.119±0.07 0.607±0.00 1.681±4.33
ENST00000439032 N/A 0.022±0.00 N/A 0.055±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002NR CIL_0002NR_0002 CGP
CIL_0004Q4 CIL_0004Q4_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0003677 IEA DNA binding
GO:0003682 ISS chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006611 ISS protein export from nucleus
GO:0007420 TAS brain development
GO:0007422 TAS peripheral nervous system development
GO:0007611 IEA learning or memory
GO:0007622 IEA rhythmic behavior
GO:0008045 IEA motor neuron axon guidance
GO:0008219 IEA cell death
GO:0014037 IEA Schwann cell differentiation
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0021569 IEA rhombomere 3 development
GO:0021612 IEA facial nerve structural organization
GO:0021660 IEA rhombomere 3 formation
GO:0021666 IEA rhombomere 5 formation
GO:0030278 IEA regulation of ossification
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032868 IEA response to insulin
GO:0035284 IEA brain segmentation
GO:0035914 IBA skeletal muscle cell differentiation
GO:0042552 IBA myelination
GO:0043066 IBA negative regulation of apoptotic process
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045444 ISS fat cell differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048168 IBA regulation of neuronal synaptic plasticity
GO:0071310 IEA cellular response to organic substance
GO:0071320 IBA cellular response to cAMP
GO:0071371 IBA cellular response to gonadotropin stimulus
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044098 egr2a protein_coding Danio_rerio
ENSMUSG00000037868 Egr2 protein_coding Mus_musculus

Loading