ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 12 (potassium/chloride transporter), member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124067 SLC12A4 9606 - 16:67943474-67969601 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316341 SLC12A4-001 67943474-67968694 protein_coding
  ENST00000422611 SLC12A4-201 67943474-67968694 protein_coding
  ENST00000537830 SLC12A4-005 67944593-67964065 protein_coding
  ENST00000541864 SLC12A4-004 67944482-67966878 protein_coding
  ENST00000570616 SLC12A4-020 67944738-67945405 nonsense_mediated_decay
  ENST00000570802 SLC12A4-018 67944485-67968553 retained_intron
  ENST00000571299 SLC12A4-008 67952216-67969601 protein_coding
  ENST00000572010 SLC12A4-003 67952242-67969192 processed_transcript
  ENST00000572037 SLC12A4-007 67944414-67968584 protein_coding
  ENST00000572476 SLC12A4-013 67949571-67950421 retained_intron
  ENST00000572766 SLC12A4-011 67949907-67951467 retained_intron
  ENST00000573023 SLC12A4-002 67947101-67968654 retained_intron
  ENST00000573702 SLC12A4-015 67950369-67951929 retained_intron
  ENST00000574665 SLC12A4-012 67949799-67951534 retained_intron
  ENST00000575857 SLC12A4-014 67945545-67947105 nonsense_mediated_decay
  ENST00000576377 SLC12A4-010 67950993-67968616 nonsense_mediated_decay
  ENST00000576462 SLC12A4-009 67957529-67968469 retained_intron
  ENST00000576513 SLC12A4-016 67948061-67950112 retained_intron
  ENST00000576616 SLC12A4-017 67944485-67968553 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000316341ENST00000537830ENST00000541864ENST00000570616ENST00000570802ENST00000572037ENST00000573023ENST00000576616
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000316341 6.883±0.37 6.686±2.32 6.957±0.00 8.025±0.00 12.861±6.55
ENST00000537830 N/A 7.245±1.80 N/A N/A 8.446±5.76
ENST00000541864 N/A 6.844±2.29 N/A N/A 12.211±7.65
ENST00000570616 97.323±2.38 N/A N/A N/A N/A
ENST00000570802 N/A N/A N/A N/A 10.342±10.40
ENST00000572037 9.611±2.48 10.716±2.85 N/A 8.768±0.00 9.899±5.78
ENST00000573023 N/A N/A N/A N/A 2.928±1.45
ENST00000576616 N/A N/A N/A 6.621±0.00 0.216±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000030 CIL_000030_0001 CGP
CIL_00003H CIL_00003H_0001 CGP
CIL_00003P CIL_00003P_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 IEA transporter activity
GO:0005765 IDA lysosomal membrane
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 TAS:IEA ion transport
GO:0006813 IEA potassium ion transport
GO:0006821 TAS chloride transport
GO:0006884 TAS cell volume homeostasis
GO:0015377 IEA cation:chloride symporter activity
GO:0015379 IEA potassium:chloride symporter activity
GO:0016020 IEA:TAS membrane
GO:0016021 IEA integral component of membrane
GO:0019901 IPI protein kinase binding
GO:0055085 IEA:TAS transmembrane transport
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014378 slc12a4 protein_coding Danio_rerio
ENSMUSG00000017765 Slc12a4 protein_coding Mus_musculus

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