ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124570 SERPINB6 9606 - 6:2948159-2972165 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335686 SERPINB6-003 2948159-2971856 protein_coding
  ENST00000380520 SERPINB6-002 2948159-2961327 protein_coding
  ENST00000380524 SERPINB6-001 2948159-2962108 protein_coding
  ENST00000380529 SERPINB6-004 2948159-2971206 protein_coding
  ENST00000380539 SERPINB6-005 2948159-2971305 protein_coding
  ENST00000380546 SERPINB6-006 2948159-2971585 protein_coding
  ENST00000612421 SERPINB6-201 2948160-2971048 protein_coding
  ENST00000616722 SERPINB6-202 2948160-2972165 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000335686ENST00000380520ENST00000380529ENST00000380539ENST00000380546
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000335686 N/A 8.486±3.23 N/A 13.182±0.00 22.334±9.82
ENST00000380520 N/A N/A N/A N/A 7.767±7.06
ENST00000380529 N/A 16.556±2.14 N/A 34.140±0.00 14.978±4.30
ENST00000380539 267.132±31.63 33.148±14.52 233.045±0.00 27.874±0.00 20.259±9.90
ENST00000380546 N/A 22.339±12.33 N/A 14.440±0.00 16.391±7.73

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000160 CIL_000160_0007 CGP
CIL_00081I CIL_00081I_0001 VISTA
CIL_00038C CIL_00038C_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0043234 IDA protein complex
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 serpinb14 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 protein_coding Danio_rerio
ENSMUSG00000042842 Serpinb6b protein_coding Mus_musculus
ENSMUSG00000047889 Serpinb6d protein_coding Mus_musculus
ENSMUSG00000052180 Serpinb6c protein_coding Mus_musculus
ENSMUSG00000060147 Serpinb6a protein_coding Mus_musculus
ENSMUSG00000069248 Serpinb6e protein_coding Mus_musculus

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