ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin-like modifier activating enzyme 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126261 UBA2 9606 + 19:34428352-34471251 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246548 UBA2-001 34428363-34471251 protein_coding
  ENST00000439527 UBA2-003 34428876-34469890 protein_coding
  ENST00000586313 UBA2-002 34428359-34464131 nonsense_mediated_decay
  ENST00000588585 UBA2-007 34467025-34469116 processed_transcript
  ENST00000590048 UBA2-005 34428373-34450364 protein_coding
  ENST00000591016 UBA2-009 34450284-34464119 protein_coding
  ENST00000592672 UBA2-004 34433260-34438743 retained_intron
  ENST00000592791 UBA2-008 34458714-34469398 protein_coding
  ENST00000592841 UBA2-011 34428484-34432033 retained_intron
  ENST00000607361 UBA2-012 34428352-34438764 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000246548ENST00000439527ENST00000586313ENST00000590048ENST00000591016ENST00000592791ENST00000607361
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000246548 N/A 4.889±1.33 N/A N/A 4.362±2.38
ENST00000439527 2.630±1.25 17.585±4.16 9.191±0.00 18.973±0.00 13.076±9.05
ENST00000586313 N/A N/A N/A N/A 5.829±4.73
ENST00000590048 N/A 17.364±2.15 N/A N/A 11.170±9.76
ENST00000591016 N/A N/A N/A N/A 27.109±0.00
ENST00000592791 8.802±0.00 19.693±3.10 N/A 32.187±0.00 31.099±5.45
ENST00000607361 N/A N/A N/A N/A 1.152±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 IBA cytosol
GO:0006464 IEA cellular protein modification process
GO:0008047 TAS enzyme activator activity
GO:0008134 IEA transcription factor binding
GO:0008152 IEA metabolic process
GO:0008641 IEA small protein activating enzyme activity
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0019948 IDA SUMO activating enzyme activity
GO:0019950 IBA SMT3-dependent protein catabolic process
GO:0031510 IBA SUMO activating enzyme complex
GO:0043085 TAS positive regulation of catalytic activity
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000052997 Uba2 protein_coding Mus_musculus

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