ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: thyroid hormone receptor, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126351 THRA 9606 + 17:40058290-40093867 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264637 THRA-001 40062810-40093867 protein_coding
  ENST00000394121 THRA-003 40062193-40093613 protein_coding
  ENST00000450525 THRA-002 40062899-40092627 protein_coding
  ENST00000546243 THRA-006 40068903-40089730 protein_coding
  ENST00000577288 THRA-007 40058290-40076912 protein_coding
  ENST00000577486 THRA-010 40072091-40077558 protein_coding
  ENST00000577637 THRA-011 40084434-40087001 retained_intron
  ENST00000578218 THRA-009 40062193-40083866 protein_coding
  ENST00000584985 THRA-005 40062810-40093867 protein_coding
  ENST00000585047 THRA-008 40061904-40077604 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000264637ENST00000450525ENST00000546243ENST00000584985
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000264637 1.713±0.00 N/A N/A 4.462±2.95
ENST00000450525 3.167±0.00 3.493±1.66 3.139±0.00 4.887±4.19
ENST00000546243 N/A 3.085±0.00 N/A N/A
ENST00000584985 N/A 4.356±0.01 3.322±0.00 3.009±2.52

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00098Y CIL_00098Y_0001 VISTA
CIL_0002PX CIL_0002PX_0001 CGP
CIL_0002KL CIL_0002KL_0001 CGP
CIL_0002L8 CIL_0002L8_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001502 IEA cartilage condensation
GO:0001503 IEA ossification
GO:0002153 IEA steroid receptor RNA activator RNA binding
GO:0002155 IEA regulation of thyroid hormone mediated signaling pathway
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003727 IEA single-stranded RNA binding
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887 IEA:IDA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007611 IEA learning or memory
GO:0008016 IEA regulation of heart contraction
GO:0008050 IEA female courtship behavior
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0009409 IEA response to cold
GO:0009755 IDA hormone-mediated signaling pathway
GO:0009887 IEA organ morphogenesis
GO:0010467 TAS gene expression
GO:0010831 IEA positive regulation of myotube differentiation
GO:0017025 IDA TBP-class protein binding
GO:0017055 IDA negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0019904 IPI protein domain specific binding
GO:0030218 IEA erythrocyte differentiation
GO:0030878 IEA thyroid gland development
GO:0031490 IEA chromatin DNA binding
GO:0032403 IEA protein complex binding
GO:0033032 IEA regulation of myeloid cell apoptotic process
GO:0042994 IEA cytoplasmic sequestering of transcription factor
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045925 IEA positive regulation of female receptivity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050994 IEA regulation of lipid catabolic process
GO:0060509 IEA Type I pneumocyte differentiation
GO:0070324 IDA thyroid hormone binding
GO:2000143 IDA negative regulation of DNA-templated transcription, initiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000151 thraa protein_coding Danio_rerio
ENSDARG00000052654 thrab protein_coding Danio_rerio
ENSMUSG00000058756 Thra protein_coding Mus_musculus

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