ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: nuclear receptor subfamily 1, group D, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126368 NR1D1 9606 - 17:40092787-40100725 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246672 NR1D1-001 40092787-40100725 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000246672
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000246672 3.713±0.37 2.816±0.83 8.667±0.00 2.957±0.00 4.269±2.79

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00098Y CIL_00098Y_0001 VISTA
CIL_0002KL CIL_0002KL_0001 CGP
CIL_0002L8 CIL_0002L8_0001 CGP
CIL_0002GG CIL_0002GG_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001222 IDA transcription corepressor binding
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003714 TAS transcription corepressor activity
GO:0004879 TAS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005978 ISS glycogen biosynthetic process
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007623 IEA circadian rhythm
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0010498 ISS proteasomal protein catabolic process
GO:0010871 IMP negative regulation of receptor biosynthetic process
GO:0019216 ISS regulation of lipid metabolic process
GO:0020037 IDA heme binding
GO:0030154 IEA cell differentiation
GO:0030425 ISS dendrite
GO:0030522 TAS intracellular receptor signaling pathway
GO:0032922 ISS circadian regulation of gene expression
GO:0034144 IMP negative regulation of toll-like receptor 4 signaling pathway
GO:0035947 IMP regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
GO:0042752 ISS regulation of circadian rhythm
GO:0043197 ISS dendritic spine
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044321 ISS response to leptin
GO:0045598 ISS regulation of fat cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0060086 ISS circadian temperature homeostasis
GO:0061178 ISS regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061469 ISS regulation of type B pancreatic cell proliferation
GO:0070859 ISS positive regulation of bile acid biosynthetic process
GO:0071222 IMP cellular response to lipopolysaccharide
GO:2000188 ISS regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033160 nr1d1 protein_coding Danio_rerio
ENSMUSG00000020889 Nr1d1 protein_coding Mus_musculus

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