ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126822 PLEKHG3 9606 + 14:64704102-64750247 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000247226 PLEKHG3-004 64704436-64750247 protein_coding
  ENST00000394691 PLEKHG3-010 64704597-64744292 protein_coding
  ENST00000471182 PLEKHG3-005 64738015-64744343 protein_coding
  ENST00000484731 PLEKHG3-012 64738035-64744345 protein_coding
  ENST00000490180 PLEKHG3-008 64730650-64744339 retained_intron
  ENST00000492928 PLEKHG3-003 64741596-64744342 processed_transcript
  ENST00000554088 PLEKHG3-014 64715703-64727756 protein_coding
  ENST00000554499 PLEKHG3-015 64723781-64730278 protein_coding
  ENST00000555982 PLEKHG3-013 64704102-64730688 protein_coding
  ENST00000556801 PLEKHG3-016 64727884-64730688 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000247226ENST00000394691ENST00000471182ENST00000484731ENST00000490180ENST00000492928
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000247226 0.013±0.00 0.174±0.00 0.061±0.00 N/A 0.082±0.04
ENST00000394691 N/A 2.255±1.23 N/A 1.168±0.00 0.852±0.59
ENST00000471182 N/A 1.671±0.47 N/A N/A 0.601±0.39
ENST00000484731 0.154±0.00 1.559±0.00 0.167±0.00 2.249±0.00 0.482±0.16
ENST00000490180 N/A N/A N/A N/A 0.382±0.16
ENST00000492928 0.507±0.00 N/A 1.068±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00010L CIL_00010L_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000052609 Plekhg3 protein_coding Mus_musculus

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