ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: helicase (DNA) B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127311 HELB 9606 + 12:66302545-66347645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000247815 HELB-001 66302545-66347645 protein_coding
  ENST00000440906 HELB-003 66302579-66338158 nonsense_mediated_decay
  ENST00000536862 HELB-006 66322740-66324519 retained_intron
  ENST00000542394 HELB-002 66302579-66338169 nonsense_mediated_decay
  ENST00000545134 HELB-004 66302580-66343643 nonsense_mediated_decay
  ENST00000545455 HELB-005 66321402-66325078 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000247815ENST00000440906ENST00000545134
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000247815 0.167±0.04 0.170±0.07 0.358±0.00 0.250±0.00 0.310±0.21
ENST00000440906 N/A 0.140±0.00 N/A N/A 0.201±0.09
ENST00000545134 N/A 0.184±0.11 N/A N/A 0.382±0.10

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0005524 IEA ATP binding
GO:0005658 IDA alpha DNA polymerase:primase complex
GO:0006260 IMP DNA replication
GO:0006261 IEA DNA-dependent DNA replication
GO:0006269 IDA DNA replication, synthesis of RNA primer
GO:0017116 IDA single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0032508 IEA DNA duplex unwinding
GO:0043141 IDA ATP-dependent 5'-3' DNA helicase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053127 helb protein_coding Danio_rerio
ENSMUSG00000020228 Helb protein_coding Mus_musculus

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